Detailed information of TA system TA234946

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 960662..960844
• Replicon: chromosome
• Accession: NZ_CP091876
• Organism: Staphylococcus aureus strain FRI-1169

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MAK06_RS05110
• Protein ID: WP_238097451.1
• Coordinates: 960749..960844 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	960662..960721 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MAK06_RS05095	959800..960177	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
MAK06_RS05100	960371..960547	+	177	Protein_967	transposase	-
MAK06_RS05105	960525..960626	-	102	WP_001791893.1	hypothetical protein	-
-	960662..960721	+	60	-	-	Antitoxin
MAK06_RS05110	960749..960844	-	96	WP_238097451.1	type I toxin-antitoxin system Fst family toxin	Toxin
MAK06_RS05115	961047..961190	+	144	WP_001549059.1	transposase	-
MAK06_RS05120	961794..962177	+	384	WP_000070811.1	hypothetical protein	-
MAK06_RS05125	962188..962364	+	177	WP_000375476.1	hypothetical protein	-
MAK06_RS05130	962366..962551	+	186	WP_000809862.1	hypothetical protein	-
MAK06_RS05135	962665..963306	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
MAK06_RS05140	963524..964075	-	552	WP_000414205.1	hypothetical protein	-
MAK06_RS05145	964173..964517	-	345	WP_000627551.1	DUF3969 family protein	-
MAK06_RS05150	964558..965184	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3494.22 Da
• Isoelectric Point: 10.4449

>T234946 WP_238097451.1 NZ_CP091876:c960844-960749 [Staphylococcus aureus]
VMLISVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T234946 NZ_LR134152:2331076-2332398 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT234946 NZ_CP091876:960662-960721 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin