Detailed information of TA system TA234927

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2363246..2363462
• Replicon: chromosome
• Accession: NZ_CP091875
• Organism: Staphylococcus aureus strain MN8

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MAK07_RS11890
• Protein ID: WP_073392962.1
• Coordinates: 2363358..2363462 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2363246..2363301 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MAK07_RS11865	2358339..2358659	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MAK07_RS11870	2358661..2359641	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
MAK07_RS11875	2359907..2360998	+	1092	WP_000495679.1	hypothetical protein	-
MAK07_RS11880	2361286..2362932	+	1647	WP_000277709.1	IS1182-like element ISSau3 family transposase	-
-	2363246..2363301	+	56	-	-	Antitoxin
MAK07_RS11890	2363358..2363462	-	105	WP_073392962.1	hypothetical protein	Toxin
MAK07_RS11895	2364142..2364300	+	159	WP_001792784.1	hypothetical protein	-
MAK07_RS11900	2364959..2365816	-	858	WP_000370937.1	HAD family hydrolase	-
MAK07_RS11905	2365884..2366666	-	783	WP_000908186.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2361286..2362932	1646

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T234927 WP_073392962.1 NZ_CP091875:c2363462-2363358 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T234927 NZ_LR134151:1568575-1568883 [Serratia plymuthica]
ATGCAGTTTACCGTATATGACAATATATATCCGGCATCGGCTTATCCATATTTGTTGGACGTTCAAAGCGATCTTATTGA
TGTTCTCTCTACTCGGTTAATGATCCCACTTTATTCTTTGGAGAAAGTCAGGGTCAAAATTTCTGCGCGTTTATGCCCGG
AAATTGAGGTAAACGGCGAAAAGTTTTTAGTTATGACGCATGAGATGGCTGCCGTGCGTATTTCGCAGATAGGGGAGGCC
GTTGGTAATGCCAATGAGCATAGGAATAAAATTAAAGCCGCCATCGATTTTCTGATTGATGGTTTTTGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT234927 NZ_CP091875:2363246-2363301 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin