Detailed information of TA system TA234905

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2096817..2097063
• Replicon: chromosome
• Accession: NZ_CP091872
• Organism: Bacillus sp. Man122

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: MAK48_RS10510
• Protein ID: WP_109789044.1
• Coordinates: 2096817..2096909 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2096890..2097063 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MAK48_RS10495	2091976..2092311	+	336	WP_009967409.1	hypothetical protein	-
MAK48_RS10500	2092358..2095963	-	3606	WP_032730401.1	P-loop NTPase fold protein	-
MAK48_RS10505	2096196..2096528	-	333	WP_026009814.1	hypothetical protein	-
MAK48_RS10510	2096817..2096909	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2096890..2097063	-	174	-	-	Antitoxin
MAK48_RS10515	2097178..2098020	-	843	WP_003231327.1	hypothetical protein	-
MAK48_RS10520	2098220..2098678	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
MAK48_RS10525	2098688..2100490	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
MAK48_RS10530	2100592..2101149	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2082802..2106480	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T234905 WP_109789044.1 NZ_CP091872:2096817-2096909 [Bacillus sp. Man122]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T234905 NZ_LR134136:1626105-1626458 [Atlantibacter hermannii]
ATGACATGGACGGTTGTATTAACACCGGAGTTTGAGCAGTGGTTTGATAAACAAGAGGCAGGGCTGCAGGATCGCATCAA
CATGATGATCACCCTGTTAGAAATTAGCGGGCCCAACCTTGGACGCCCCCACGTTGACACACTCGTTGGATCGCGTTACC
CAAATATGAAAGAGCTACGTATACAATATGCCGGTGAGCCATGGCGCGTAGGGTTTGCCTTTAATCACAGACAGCAAGCT
GTACTGTTATATGGCGGCCAAAAAACGGGAAAAAAGCGCTTTTATACATTGTTAATTGCACAAGTCGATGCGATTTTCGC
ACGCGATCTCGCCCGTAAAAAGGAGACTCTATGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT234905 NZ_CP091872:c2097063-2096890 [Bacillus sp. Man122]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin