Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 232315..232823 Replicon chromosome
Accession NZ_CP091864
Organism Corynebacterium pseudodiphtheriticum strain PC1130

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag L9H78_RS01005 Protein ID WP_249620204.1
Coordinates 232315..232575 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L9H78_RS01010 Protein ID WP_249620205.1
Coordinates 232572..232823 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L9H78_RS00990 (L9H78_00990) 227700..228461 - 762 WP_249620201.1 TetR/AcrR family transcriptional regulator -
L9H78_RS00995 (L9H78_00995) 228458..230002 - 1545 WP_249620202.1 MFS transporter -
L9H78_RS01000 (L9H78_01000) 230282..232318 + 2037 WP_249620203.1 BCCT family transporter -
L9H78_RS01005 (L9H78_01005) 232315..232575 - 261 WP_249620204.1 Txe/YoeB family addiction module toxin Toxin
L9H78_RS01010 (L9H78_01010) 232572..232823 - 252 WP_249620205.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L9H78_RS01015 (L9H78_01015) 233031..233978 + 948 WP_249620701.1 hypothetical protein -
L9H78_RS01020 (L9H78_01020) 234006..235403 - 1398 WP_249620206.1 MFS transporter -
L9H78_RS01025 (L9H78_01025) 235543..236583 + 1041 WP_249620207.1 hypothetical protein -
L9H78_RS01030 (L9H78_01030) 236630..237361 - 732 WP_049167580.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island erm(X) - 223869..246965 23096


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10497.96 Da        Isoelectric Point: 10.1603

>T234902 WP_249620204.1 NZ_CP091864:c232575-232315 [Corynebacterium pseudodiphtheriticum]
MKLVWTESAWEDYTWWQTEDRKVLKRINRLIKEIQRNGNSGIGKPEPLKHGFQGYWSRRITDEHRLVYKIFGDEVRIASC
RYHYGR

Download         Length: 261 bp

>T234902 NZ_LR134136:312968-313336 [Atlantibacter hermannii]
ATGACAATTCAGTTTATCTCAGCGGAAGAGATAATTCGTTTTCATGACAGATTGCTGGCCGTCACGCCAGGCGTACCCGG
TATGGTCGATCCGGGTCGGGCGGAAGCACTGTTATACCGTGTGCTTAACAAATACAAGTATGAAGGCGTTAATGACCTCT
GGCTTTTGGCAGCAATGCACCTGCTGGCTATTTCCCGAGGGCATATCTTCAATGATGGCAATAAACGCACGGCGCTGTTT
ATTACCTTGTTGTTCCTTAAGCGCAATGGGATAACGCTTCCCGCCAACCCGGCATTTGTCGAGTTAACGGTGGCGGCGGC
GGCAGGACAACTTAGCCTTGAAGAGATAGCGCGTCAGTTACGAAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9386.46 Da        Isoelectric Point: 4.3016

>AT234902 WP_249620205.1 NZ_CP091864:c232823-232572 [Corynebacterium pseudodiphtheriticum]
MKTMSYSDSRAHYAEMLDTVTDDREEVIITRAGHEPVVVVSLDDYESLKETAYLLKSPANARRLLASIEQLENGEGTQRD
LLE

Download         Length: 252 bp

>AT234902 NZ_LR134136:312750-312971 [Atlantibacter hermannii]
ATGCAAACCATGAACTATAGCGAAGCGCGCCAGAATCTTGCTGCCGCGCTCGAGACAGCTGCGCTGGGTACGCCTGTTAC
TATCACCCGTCGGGGCCACAAACCTGCGGTAATTATTAGCGCCGAAGAATTCGAACGTTATCAACAAGCAAAGATGGATG
CCGAATTTGCCGCCATCATGGCTATTCATGGCAATGAAATCAGGGAACTTGCCGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References