Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | hok-sok/- |
| Location | 40369..40633 | Replicon | 2 plasmid p2-3 |
| Accession | NZ_CP091573 | ||
| Organism | Salmonella enterica strain | ||
Toxin (Protein)
| Gene name | pndA | Uniprot ID | U9Z417 |
| Locus tag | INN74_RS25405 | Protein ID | WP_001387489.1 |
| Coordinates | 40481..40633 (+) | Length | 51 a.a. |
Antitoxin (RNA)
| Gene name | pndB | ||
| Locus tag | - | ||
| Coordinates | 40369..40429 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| INN74_RS25390 (36471) | 36471..37541 | - | 1071 | WP_012783932.1 | IncI1-type conjugal transfer protein TrbB | - |
| INN74_RS25395 (37560) | 37560..38768 | - | 1209 | WP_001703845.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (38948) | 38948..39005 | - | 58 | NuclAT_1 | - | - |
| - (38948) | 38948..39005 | - | 58 | NuclAT_1 | - | - |
| - (38948) | 38948..39005 | - | 58 | NuclAT_1 | - | - |
| - (38948) | 38948..39005 | - | 58 | NuclAT_1 | - | - |
| INN74_RS25400 (39075) | 39075..39854 | - | 780 | WP_275450201.1 | protein FinQ | - |
| - (40369) | 40369..40429 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (40369) | 40369..40429 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (40369) | 40369..40429 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (40369) | 40369..40429 | - | 61 | NuclAT_0 | - | Antitoxin |
| INN74_RS25405 (40481) | 40481..40633 | + | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin |
| INN74_RS25410 (40705) | 40705..40956 | - | 252 | WP_001291964.1 | hypothetical protein | - |
| INN74_RS26575 (41457) | 41457..41552 | + | 96 | WP_000609148.1 | DinQ-like type I toxin DqlB | - |
| INN74_RS25420 (41617) | 41617..41793 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| INN74_RS25425 (42185) | 42185..42394 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| INN74_RS25430 (42466) | 42466..43128 | - | 663 | WP_012783935.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| INN74_RS25435 (43199) | 43199..45367 | - | 2169 | WP_015508354.1 | DotA/TraY family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | blaCTX-M-55 | - | 1..86718 | 86718 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5761.10 Da Isoelectric Point: 8.7948
>T233880 WP_001387489.1 NZ_CP091573:40481-40633 [Salmonella enterica]
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T233880 NZ_CP091573:40481-40633 [Salmonella enterica]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCGTCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCGTCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA
Antitoxin
Download Length: 61 bp
>AT233880 NZ_CP091573:c40429-40369 [Salmonella enterica]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
