Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 15414..15672 Replicon chromosome
Accession NC_011748
Organism Escherichia coli 55989

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag EC55989_RS00080 Protein ID WP_000809170.1
Coordinates 15414..15566 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 15615..15672 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EC55989_RS00060 10655..11368 - 714 WP_001102379.1 acidic protein MsyB -
EC55989_RS00065 11394..11798 - 405 WP_000843559.1 DUF2541 family protein -
EC55989_RS00070 12175..14091 + 1917 WP_000516135.1 molecular chaperone DnaK -
EC55989_RS00075 14180..15310 + 1131 WP_001118464.1 molecular chaperone DnaJ -
EC55989_RS00080 15414..15566 - 153 WP_000809170.1 type I toxin-antitoxin system toxin MokC Toxin
- 15615..15672 + 58 - - Antitoxin
EC55989_RS00085 16152..17318 + 1167 WP_000681360.1 Na+/H+ antiporter NhaA -
EC55989_RS00090 17384..18283 + 900 WP_001300855.1 transcriptional activator NhaR -
EC55989_RS00095 18322..19281 - 960 WP_000871667.1 hypothetical protein -
EC55989_RS00100 19294..20625 - 1332 Protein_18 fimbria/pilus outer membrane usher protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5489.51 Da        Isoelectric Point: 7.1312

>T23388 WP_000809170.1 NC_011748:c15566-15414 [Escherichia coli 55989]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHTRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T23388 NC_011748:c15566-15414 [Escherichia coli 55989]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACACCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT23388 NC_011748:15615-15672 [Escherichia coli 55989]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References