Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3915097..3915319 Replicon chromosome
Accession NC_011742
Organism Escherichia coli S88

Toxin (Protein)


Gene name ldrD Uniprot ID A0A0D6GD35
Locus tag ECS88_RS27465 Protein ID WP_000170745.1
Coordinates 3915097..3915204 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3915261..3915319 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECS88_RS21295 3910150..3910338 - 189 WP_001063314.1 YhjR family protein -
ECS88_RS21300 3910611..3912182 + 1572 WP_001204957.1 cellulose biosynthesis protein BcsE -
ECS88_RS21305 3912179..3912370 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ECS88_RS21310 3912367..3914046 + 1680 WP_000191616.1 cellulose biosynthesis protein BcsG -
ECS88_RS21315 3914132..3914239 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
ECS88_RS27460 3914615..3914722 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
ECS88_RS27465 3915097..3915204 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3915261..3915319 + 59 - - Antitoxin
ECS88_RS21345 3915680..3916951 + 1272 WP_001332306.1 amino acid permease -
ECS88_RS21350 3916981..3917985 - 1005 WP_000103579.1 dipeptide ABC transporter ATP-binding subunit DppF -
ECS88_RS21355 3917982..3918965 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
ECS88_RS21360 3918976..3919878 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3855.68 Da        Isoelectric Point: 9.0157

>T23376 WP_000170745.1 NC_011742:c3915204-3915097 [Escherichia coli S88]
MTLAELGMAFWHDLAAPVIAGILASMIVSWLNKRK

Download         Length: 108 bp

>T23376 NC_011742:c3915204-3915097 [Escherichia coli S88]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT23376 NC_011742:3915261-3915319 [Escherichia coli S88]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D6GD35

Antitoxin

Download structure file

References