Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3914132..3914354 Replicon chromosome
Accession NC_011742
Organism Escherichia coli S88

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag ECS88_RS21315 Protein ID WP_001295224.1
Coordinates 3914132..3914239 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3914296..3914354 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECS88_RS21290 3909386..3910138 - 753 WP_000279545.1 cellulose biosynthesis protein BcsQ -
ECS88_RS21295 3910150..3910338 - 189 WP_001063314.1 YhjR family protein -
ECS88_RS21300 3910611..3912182 + 1572 WP_001204957.1 cellulose biosynthesis protein BcsE -
ECS88_RS21305 3912179..3912370 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ECS88_RS21310 3912367..3914046 + 1680 WP_000191616.1 cellulose biosynthesis protein BcsG -
ECS88_RS21315 3914132..3914239 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3914296..3914354 + 59 - - Antitoxin
ECS88_RS27460 3914615..3914722 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
ECS88_RS27465 3915097..3915204 - 108 WP_000170745.1 type I toxin-antitoxin system toxin Ldr family protein -
ECS88_RS21345 3915680..3916951 + 1272 WP_001332306.1 amino acid permease -
ECS88_RS21350 3916981..3917985 - 1005 WP_000103579.1 dipeptide ABC transporter ATP-binding subunit DppF -
ECS88_RS21355 3917982..3918965 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T23372 WP_001295224.1 NC_011742:c3914239-3914132 [Escherichia coli S88]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T23372 NC_011742:c3914239-3914132 [Escherichia coli S88]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 59 bp

>AT23372 NC_011742:3914296-3914354 [Escherichia coli S88]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References