Detailed information of TA system TA233515

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2703870..2704132
• Replicon: chromosome
• Accession: NZ_CP091525
• Organism: Staphylococcus aureus strain N09CSA16

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: L4X60_RS13340
• Protein ID: WP_001802298.1
• Coordinates: 2703870..2703974 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2703969..2704132 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L4X60_RS13325	2700667..2701449	+	783	WP_000908182.1	ABC transporter ATP-binding protein	-
L4X60_RS13330	2701517..2702374	+	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
L4X60_RS13335	2703032..2703190	-	159	WP_001792784.1	hypothetical protein	-
L4X60_RS13340	2703870..2703974	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2703969..2704132	-	164	-	-	Antitoxin
L4X60_RS13350	2704407..2705498	-	1092	WP_000495669.1	hypothetical protein	-
L4X60_RS13355	2705764..2706741	-	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
L4X60_RS13360	2706743..2707063	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
L4X60_RS13365	2707215..2707880	+	666	WP_001024095.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T233515 WP_001802298.1 NZ_CP091525:2703870-2703974 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T233515 NZ_HG969191:c1114028-1113759 [Bartonella henselae]
TTGGCTTGGACGATTAGATATGAAAAAAAAGCTCTCAGTTTTTTAAAAAAATGCGATAAAAAAGAAGCACGGCGGATTGT
TGATTTTTTAGATCAACACGTTGCTCCTCTTGAAGATGTGCGTGTAATAGGTAAGCCCTTAAAAGGACAATTCCCAGGTT
TATGGAGATATCGTGTAGGAGATTACAGGATACTTTGTGAACTCTATGATAAGGAGCTTGTCGTATTAGTTTTGGCTGTT
GGACATAGAAAAAATATATATAAAGGTTAA

Antitoxin

Nucleotide

• Length: 164 bp

>AT233515 NZ_CP091525:c2704132-2703969 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin