Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1065931..1066583 Replicon chromosome
Accession NZ_CP091519
Organism Alysiella crassa strain S6

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LVJ80_RS05470 Protein ID WP_034293502.1
Coordinates 1065931..1066272 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LVJ80_RS05475 Protein ID WP_244773558.1
Coordinates 1066380..1066583 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVJ80_RS05450 (LVJ80_05450) 1061120..1062181 + 1062 WP_034293497.1 glycosyltransferase family 9 protein -
LVJ80_RS05455 (LVJ80_05455) 1062346..1063971 - 1626 WP_034293498.1 CTP synthase -
LVJ80_RS15285 1064378..1065180 + 803 Protein_1078 alanine:cation symporter family protein -
LVJ80_RS15290 1065214..1065447 + 234 WP_280517581.1 hypothetical protein -
LVJ80_RS15295 1065360..1065770 + 411 WP_280517576.1 alanine:cation symporter family protein -
LVJ80_RS05465 (LVJ80_05465) 1065767..1065931 - 165 WP_156961051.1 hypothetical protein -
LVJ80_RS05470 (LVJ80_05470) 1065931..1066272 + 342 WP_034293502.1 toxin Toxin
LVJ80_RS05475 (LVJ80_05475) 1066380..1066583 + 204 WP_244773558.1 helix-turn-helix domain-containing protein Antitoxin
LVJ80_RS05480 (LVJ80_05480) 1066647..1067288 - 642 WP_051968533.1 inner membrane CreD family protein -
LVJ80_RS05485 (LVJ80_05485) 1067631..1068305 + 675 WP_034295893.1 response regulator -
LVJ80_RS05490 (LVJ80_05490) 1068299..1069267 + 969 WP_034295895.1 histidine kinase dimerization/phospho-acceptor domain-containing protein -
LVJ80_RS05495 (LVJ80_05495) 1069496..1070836 - 1341 WP_244773563.1 beta-Ala-His dipeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(6-51)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13039.72 Da        Isoelectric Point: 7.1641

>T233470 WP_034293502.1 NZ_CP091519:1065931-1066272 [Alysiella crassa]
MASIFNAEWDEFSAKSNREQIVISPYADFQNELMENPEKGDLIQGTGGLRKIRVADPKCQKGKRGGSRVIYYWHLNQAQF
VLFTVYGKNQQDDLNHEQRLLAQLLQVIKDNQP

Download         Length: 342 bp

>T233470 NZ_HG941718:c1695440-1694118 [Escherichia coli O25b:H4-ST131]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCAGCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAACGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTACGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGATCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7549.74 Da        Isoelectric Point: 11.0544

>AT233470 WP_244773558.1 NZ_CP091519:1066380-1066583 [Alysiella crassa]
VVISPDEIRAIREQLNLSQAVFAQKLRMSVRTYQGWEQGKTRPNSQAALLLKMVAQSPQTFHNIAAI

Download         Length: 204 bp

>AT233470 NZ_HG941718:c1695706-1695440 [Escherichia coli O25b:H4-ST131]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAGTTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTGACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAAGCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References