Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 51040..51698 Replicon chromosome
Accession NZ_CP091454
Organism Acinetobacter baumannii strain AB329

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LGY76_RS19550 Protein ID WP_000312250.1
Coordinates 51339..51698 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LGY76_RS19545 Protein ID WP_001096429.1
Coordinates 51040..51339 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGY76_RS19505 46064..47344 + 1281 WP_001093570.1 hypothetical protein -
LGY76_RS19510 47449..47706 + 258 WP_000834290.1 hypothetical protein -
LGY76_RS19515 47711..48283 + 573 WP_000443897.1 hypothetical protein -
LGY76_RS19520 48259..48438 + 180 WP_000387630.1 hypothetical protein -
LGY76_RS19525 48455..49084 + 630 WP_000701003.1 hypothetical protein -
LGY76_RS19530 49124..49342 + 219 WP_001043201.1 hypothetical protein -
LGY76_RS19535 49362..49916 + 555 WP_000790084.1 hypothetical protein -
LGY76_RS19540 49966..50502 + 537 WP_000731978.1 hypothetical protein -
LGY76_RS19545 51040..51339 - 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
LGY76_RS19550 51339..51698 - 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGY76_RS19555 51899..52465 + 567 WP_000710385.1 hypothetical protein -
LGY76_RS19565 53952..54650 + 699 WP_000873188.1 hypothetical protein -
LGY76_RS19570 54789..55172 + 384 WP_000654348.1 hypothetical protein -
LGY76_RS19575 55239..55997 + 759 WP_001053127.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T233345 WP_000312250.1 NZ_CP091454:c51698-51339 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

>T233345 NZ_HG813240:c753925-753617 [Mycobacterium tuberculosis 49-02]
ATGCGGCGCGGTGAATTGTGGTTTGCCGCCACACCTGGTGGTGACAGACCAGTACTTGTCCTTACCAGAGATCCGGTGGC
AGACCGCATCGGCGCGGTCGTTGTGGTGGCCCTAACCCGCACCCGCCGAGGCCTGGTGTCGGAATTGGAGCTCACGGCCG
TCGAAAACCGTGTTCCGAGCGACTGCGTCGTCAACTTCGACAACATTCATACGTTGCCACGCACCGCATTCCGACGCCGC
ATCACCCGGCTGTCCCCGGCCCGCCTGCACGAAGCCTGTCAAACACTCCGGGCGAGCACGGGGTGTTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT233345 WP_001096429.1 NZ_CP091454:c51339-51040 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp

>AT233345 NZ_HG813240:c754157-753912 [Mycobacterium tuberculosis 49-02]
ATGCTCAGCTTCCGCGCCGACGACCACGACGTCGACCTGGCCGACGCGTGGGCGCGTCGCCTACACATCGGCCGCTCCGA
GCTGCTGCGCGATGCGCTGCGACGTCACTTGGCCGCGCTGGCCGCGGACCAGGATGTCCAGGCCTACACCGAGCGACCGT
TGACGGACGACGAGAACGCACTGGCTGAGATCGCCGACTGGGGGCCGGCGGAGGACTGGGCCGACTGGGCCGATGCGGCG
CGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References