Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF1/-
Location 19731..20069 Replicon chromosome
Accession NZ_CP091412
Organism Staphylococcus aureus strain ATR-20003

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag L3I92_RS00105 Protein ID WP_011447039.1
Coordinates 19731..19907 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 19895..20069 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3I92_RS00085 14966..18751 + 3786 WP_237269210.1 phage tail spike protein -
L3I92_RS00090 18741..18884 + 144 WP_031783159.1 hypothetical protein -
L3I92_RS00095 18940..19227 + 288 WP_001040254.1 hypothetical protein -
L3I92_RS00100 19285..19581 + 297 WP_000539688.1 DUF2951 domain-containing protein -
L3I92_RS00105 19731..19907 + 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 19895..20069 - 175 - - Antitoxin
L3I92_RS00115 20119..20373 + 255 WP_000611512.1 phage holin -
L3I92_RS00120 20385..21140 + 756 WP_237269211.1 CHAP domain-containing protein -
L3I92_RS00125 21633..22802 - 1170 Protein_24 AbgT family transporter -
L3I92_RS00130 23038..23856 + 819 WP_000824951.1 SDR family oxidoreductase -
L3I92_RS00135 23957..24724 + 768 WP_049295992.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1..21140 21139


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T233269 WP_011447039.1 NZ_CP091412:19731-19907 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 175 bp

>AT233269 NZ_CP091412:c20069-19895 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCC
GTTAAAAAGACGGTGACTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTGTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References