Detailed information of TA system TA233012

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 299715..299910
• Replicon: chromosome
• Accession: NZ_CP091237
• Organism: Enterococcus faecalis strain 1521

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LQ062_RS01515
• Protein ID: WP_015543884.1
• Coordinates: 299815..299910 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	299715..299779 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ062_RS01500 (295327)	295327..297075	+	1749	WP_002419225.1	PTS transporter subunit EIIC	-
LQ062_RS01505 (297066)	297066..299099	+	2034	WP_002383677.1	BglG family transcription antiterminator	-
LQ062_RS01510 (299110)	299110..299544	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
- (299715)	299715..299779	+	65	NuclAT_12	-	Antitoxin
LQ062_RS01515 (299815)	299815..299910	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LQ062_RS01520 (300156)	300156..301928	+	1773	WP_010816286.1	PTS mannitol-specific transporter subunit IIBC	-
LQ062_RS01525 (301943)	301943..302380	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LQ062_RS01530 (302395)	302395..303549	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LQ062_RS01535 (303618)	303618..304733	-	1116	WP_219259638.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T233012 WP_015543884.1 NZ_CP091237:c299910-299815 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T233012 NZ_CP128516:2313299-2313631 [Mannheimia haemolytica]
ATGAAACGTGGCGATATTTACTGGCTCGATCTTGATCCAACCTTAGGACACGAACAATCAGGCTTCCGCCCCGTTGTAAT
TGTTTCCGCAACTGCATTTAATCTAGCCAGTAAACTGCCTGTGGTTGTGCCGATTACTAACGGTGGAGCTTTTGCTGAAA
GACTGGGCTTTGCCGTTTCATTAAAAGATGCCGGCTTAAAAACAACAGGGATTATTCGATGCGATCAACCTCGCACAGTC
GATATTGCACAACGCCATGGAAAATTTATCGAAGCCTTACCCGAAAGCCTACTTGATGAAATTATGGCAAGGGTTTCAGT
GATTTTTGAGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT233012 NZ_CP091237:299715-299779 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin