Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2828004..2828340 Replicon chromosome
Accession NZ_CP091235
Organism Enterococcus faecalis strain 705

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag LQ054_RS13580 Protein ID WP_002396786.1
Coordinates 2828004..2828147 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2828291..2828340 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ054_RS13560 2823220..2823435 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
LQ054_RS13565 2823574..2824566 + 993 WP_002378862.1 biotin--[acetyl-CoA-carboxylase] ligase -
LQ054_RS13570 2824733..2825371 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
LQ054_RS13575 2826056..2827672 + 1617 WP_002378864.1 phosphatase PAP2/LCP family protein -
LQ054_RS13580 2828004..2828147 + 144 WP_002396786.1 putative holin-like toxin Toxin
- 2828291..2828340 + 50 - - Antitoxin
LQ054_RS13585 2828342..2833033 - 4692 WP_116491824.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T233010 WP_002396786.1 NZ_CP091235:2828004-2828147 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

>T233010 NZ_CP128516:1759564-1759788 [Mannheimia haemolytica]
ATGGTAGTAAAAATCCTAAAGCGGAAATCTCAAAAGACACTACAACAAATCTACACCCAGCCTATTTCTGCCAATATTAA
ATGGACAAATATAGAAGCTCTTTTTCTAGAGTTAGGAGCAGAAATAGAAGAACGAGAAGGGAGCAGAATTGCAGTTGTTT
TATTTCAACAGGTCAGAGTATTTCATCGCCCACACCCGAATCCTGATACAGATAAGGGGCGGTAG

Antitoxin


Download         Length: 50 bp

>AT233010 NZ_CP091235:2828291-2828340 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References