Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2670310..2670534 | Replicon | chromosome |
Accession | NZ_CP091235 | ||
Organism | Enterococcus faecalis strain 705 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | LQ054_RS12860 | Protein ID | WP_224561205.1 |
Coordinates | 2670433..2670534 (-) | Length | 34 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2670310..2670488 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQ054_RS12835 | 2665957..2666910 | - | 954 | WP_002359060.1 | siderophore ABC transporter substrate-binding protein | - |
LQ054_RS12840 | 2666949..2667704 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
LQ054_RS12845 | 2667701..2668666 | - | 966 | WP_002371665.1 | iron chelate uptake ABC transporter family permease subunit | - |
LQ054_RS12850 | 2668663..2669610 | - | 948 | WP_002354960.1 | iron chelate uptake ABC transporter family permease subunit | - |
LQ054_RS12855 | 2669795..2670247 | + | 453 | WP_002378807.1 | YueI family protein | - |
- | 2670310..2670488 | + | 179 | - | - | Antitoxin |
LQ054_RS12860 | 2670433..2670534 | - | 102 | WP_224561205.1 | putative holin-like toxin | Toxin |
LQ054_RS12865 | 2670725..2672995 | - | 2271 | WP_002378809.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
LQ054_RS12870 | 2673166..2673672 | + | 507 | WP_002378810.1 | cysteine hydrolase family protein | - |
LQ054_RS12875 | 2673862..2674758 | + | 897 | WP_002365354.1 | YitT family protein | - |
LQ054_RS12880 | 2674809..2675207 | - | 399 | WP_002354951.1 | glyoxalase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 34 a.a. Molecular weight: 3629.37 Da Isoelectric Point: 4.5869
>T233005 WP_224561205.1 NZ_CP091235:c2670534-2670433 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK
MSIEATLELMISFAAFVALLIFGILEATKNDKK
Download Length: 102 bp
>T233005 NZ_CP128516:272872-273261 [Mannheimia haemolytica]
ATGTATATGTTAGATACGAATACTGTAAGCTATTTTTTTCGTGGAAATGCAAATGTGGTGGCGAAATTGAAGTCCATTAA
TCCTGAGAGGCTTTGTATTTCATCTGTAACTGCTGCTGAATTGGTTTATGGTGTGGCGAAAAGAAATAATGGGCAGCTTT
CTCAATTTTTAGATTATTTTTTATCGAGTGTAAAGGTTTTAGATTGGAATTATCGTTGTGCTGAACTTTATGGAAAGTTA
CGGGCAGAGATGGAGAAAAATGGCAAAGTAATGGGCGTGCAGGATCAAATGATTGCTAGTCACGCTCTTGCTGAAGAGTG
TATTTTAGTTTCTAGTGATCAGGCATTTAAAATGGTACCTGATCTGAAATTGGAGAATTGGTTACACTAA
ATGTATATGTTAGATACGAATACTGTAAGCTATTTTTTTCGTGGAAATGCAAATGTGGTGGCGAAATTGAAGTCCATTAA
TCCTGAGAGGCTTTGTATTTCATCTGTAACTGCTGCTGAATTGGTTTATGGTGTGGCGAAAAGAAATAATGGGCAGCTTT
CTCAATTTTTAGATTATTTTTTATCGAGTGTAAAGGTTTTAGATTGGAATTATCGTTGTGCTGAACTTTATGGAAAGTTA
CGGGCAGAGATGGAGAAAAATGGCAAAGTAATGGGCGTGCAGGATCAAATGATTGCTAGTCACGCTCTTGCTGAAGAGTG
TATTTTAGTTTCTAGTGATCAGGCATTTAAAATGGTACCTGATCTGAAATTGGAGAATTGGTTACACTAA
Antitoxin
Download Length: 179 bp
>AT233005 NZ_CP091235:2670310-2670488 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAGTGCAACAA
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAGTGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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