233002

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2670273..2670534 Replicon chromosome
Accession NZ_CP091235
Organism Enterococcus faecalis strain 705

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag LQ054_RS12860 Protein ID WP_224561205.1
Coordinates 2670433..2670534 (-) Length 34 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2670273..2670484 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ054_RS12835 2665957..2666910 - 954 WP_002359060.1 siderophore ABC transporter substrate-binding protein -
LQ054_RS12840 2666949..2667704 - 756 WP_002354962.1 ATP-binding cassette domain-containing protein -
LQ054_RS12845 2667701..2668666 - 966 WP_002371665.1 iron chelate uptake ABC transporter family permease subunit -
LQ054_RS12850 2668663..2669610 - 948 WP_002354960.1 iron chelate uptake ABC transporter family permease subunit -
LQ054_RS12855 2669795..2670247 + 453 WP_002378807.1 YueI family protein -
- 2670273..2670484 + 212 - - Antitoxin
LQ054_RS12860 2670433..2670534 - 102 WP_224561205.1 putative holin-like toxin Toxin
LQ054_RS12865 2670725..2672995 - 2271 WP_002378809.1 bifunctional glutamate--cysteine ligase/glutathione synthetase -
LQ054_RS12870 2673166..2673672 + 507 WP_002378810.1 cysteine hydrolase family protein -
LQ054_RS12875 2673862..2674758 + 897 WP_002365354.1 YitT family protein -
LQ054_RS12880 2674809..2675207 - 399 WP_002354951.1 glyoxalase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-33)


Sequences


Toxin        


Download         Length: 34 a.a.        Molecular weight: 3629.37 Da        Isoelectric Point: 4.5869

>T233002 WP_224561205.1 NZ_CP091235:c2670534-2670433 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK

Download         Length: 102 bp

>T233002 NZ_CP128515:c1879266-1878970 [Mannheimia haemolytica]
ATGTATATAGATTTGCAATATGCTGTGCCGTTATTGTTTGAATACGACCCGAACAAAAGCCAAATTAATTTAGCCAAATA
TGGTATTGATTTTGAACAGGCAAAGTTGCTTTGGGAAGATGAACGAAAAGTTGTACTGGAGGCTTGCATTGAACCCGAAT
TACGCTATTTCCTGATTGGCAAGATTTATGATAAATATTGGACAGCGTTTTTTACACCAAGAAATGATGTTATTCGTTTA
ATTTCAGTTAGACGTTCCCGTAAAAAAGAGATCTCATACTATGAGAAATACCATTAG

Antitoxin


Download         Length: 212 bp

>AT233002 NZ_CP091235:2670273-2670484 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGG
TTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References