Detailed information of TA system TA232994

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 300100..300295
• Replicon: chromosome
• Accession: NZ_CP091235
• Organism: Enterococcus faecalis strain 705

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: LQ054_RS01520
• Protein ID: WP_015543884.1
• Coordinates: 300200..300295 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	300100..300165 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ054_RS01505	295731..297473	+	1743	WP_002401739.1	PTS transporter subunit EIIC	-
LQ054_RS01510	297464..299497	+	2034	WP_002355275.1	BglG family transcription antiterminator	-
LQ054_RS01515	299508..299942	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	300100..300165	+	66	-	-	Antitoxin
LQ054_RS01520	300200..300295	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
LQ054_RS01525	300541..302313	+	1773	WP_002391520.1	PTS mannitol-specific transporter subunit IIBC	-
LQ054_RS01530	302328..302765	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
LQ054_RS01535	302780..303934	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
LQ054_RS01540	304003..305118	-	1116	WP_002377910.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-119)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T232994 WP_015543884.1 NZ_CP091235:c300295-300200 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T232994 NZ_CP128512:c1769517-1769128 [Mannheimia haemolytica]
ATGTATATGTTAGATACGAATACTGTAAGCTATTTTTTTCGTGGAAATGCAAATGTGGTGGCGAAATTGAAGTCCATTAA
TCCTGAGAGGCTTTGTATTTCATCTGTAACTGCTGCTGAATTGGTTTATGGTGTGGCGAAAAGAAATAATGGGCAGCTTT
CTCAATTTTTAGATTATTTTTTATCGAGTGTAAAGGTTTTAGATTGGAATTATCGTTGTGCTGAACTTTATGGAAAGTTA
CGGGCAGAGATGGAGAAAAATGGCAAAGTAATGGGCGTGCAGGATCAAATGATTGCTAGTCACGCTCTTGCTGAAGAGTG
TATTTTAGTTTCTAGCGATCAGGCATTTAAAATGGTACCTGATCTGAAATTGGAGAATTGGTTACACTAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT232994 NZ_CP091235:300100-300165 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin