Detailed information of TA system TA232979

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2859727..2859993
• Replicon: chromosome
• Accession: NZ_CP091231
• Organism: Enterococcus faecalis strain 732

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: LQ055_RS14140
• Protein ID: WP_002411240.1
• Coordinates: 2859727..2859876 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2859809..2859993 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ055_RS14120	2854848..2855063	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
LQ055_RS14125	2855202..2856194	+	993	WP_002389493.1	biotin--[acetyl-CoA-carboxylase] ligase	-
LQ055_RS14130	2856458..2857096	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
LQ055_RS14135	2857782..2859398	+	1617	WP_002389442.1	phosphatase PAP2/LCP family protein	-
LQ055_RS14140	2859727..2859876	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2859809..2859993	-	185	-	-	Antitoxin
LQ055_RS14145	2859995..2860135	+	141	WP_073340360.1	putative holin-like toxin	-
LQ055_RS14150	2860366..2860509	+	144	WP_002381035.1	putative holin-like toxin	-
LQ055_RS14155	2860704..2864531	-	3828	WP_010816211.1	WxL domain-containing protein	-
LQ055_RS14160	2864518..2864880	-	363	WP_002378868.1	LPXTG cell wall anchor domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T232979 WP_002411240.1 NZ_CP091231:2859727-2859876 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

>T232979 NZ_CP128508:2430692-2430973 [Pseudomonas asiatica]
ATGACCTATAAACTCGAATTCCTGCCTTCGGCACTGAAAGAGTGGGGCAAGCTAGGCCACACCGTGCGCGAACAGATCAA
GAAAAAACTCGCCGAGCGCCTGCAGTCACCCAAGGTACAGGCCGACGCGCTGCGTGACCTGCCGAACCACTACAAAATCA
AGCTCAAGGCCTCTGGATATCGCCTCGTCTATCGAGTCGAGGACGAGCGGATCGTTGTAGTGGTGGTATCGGTTGGCAAA
CGCGAGCGTAGCGAGGTGTATCGATCCGCTCAGAAGCGGTAA

Antitoxin

Nucleotide

• Length: 185 bp

>AT232979 NZ_CP091231:c2859993-2859809 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin