Detailed information of TA system TA232975

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2786868..2787130
• Replicon: chromosome
• Accession: NZ_CP091231
• Organism: Enterococcus faecalis strain 732

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: LQ055_RS13810
• Protein ID: WP_002367458.1
• Coordinates: 2786987..2787130 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2786868..2787054 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ055_RS13795	2782325..2785069	+	2745	WP_025189146.1	glycosyl hydrolase family 65 protein	-
LQ055_RS13800	2785084..2785734	+	651	WP_002389419.1	beta-phosphoglucomutase	-
LQ055_RS13805	2786154..2786747	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	2786868..2787054	+	187	-	-	Antitoxin
LQ055_RS13810	2786987..2787130	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
LQ055_RS13815	2787362..2788333	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
LQ055_RS13820	2788508..2788945	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
LQ055_RS13825	2789078..2789632	-	555	WP_002354869.1	Maf family protein	-
LQ055_RS13830	2789657..2791789	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T232975 WP_002367458.1 NZ_CP091231:c2787130-2786987 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

>T232975 NZ_CP128507:3576480-3577058 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
TCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGATAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGCTCGGCGCGACGCCTAG

Antitoxin

Nucleotide

• Length: 187 bp

>AT232975 NZ_CP091231:2786868-2787054 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin