Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 13989..14247 Replicon chromosome
Accession NC_011740
Organism Escherichia fergusonii ATCC 35469

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag EFER_RS00320 Protein ID WP_000809168.1
Coordinates 13989..14141 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 14190..14247 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFER_RS00300 9055..9642 + 588 WP_002431696.1 molybdopterin adenylyltransferase -
EFER_RS00305 9676..10242 - 567 WP_000528529.1 acetate uptake transporter -
EFER_RS00310 10750..12666 + 1917 WP_000516135.1 molecular chaperone DnaK -
EFER_RS00315 12755..13885 + 1131 WP_001118464.1 molecular chaperone DnaJ -
EFER_RS00320 13989..14141 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 14190..14247 + 58 - - Antitoxin
EFER_RS00325 14682..15848 + 1167 WP_000681374.1 Na+/H+ antiporter NhaA -
EFER_RS00330 15916..16815 + 900 WP_000019049.1 transcriptional activator NhaR -
EFER_RS00335 16911..17174 - 264 WP_001274021.1 30S ribosomal protein S20 -
EFER_RS00340 17277..17495 + 219 WP_012599853.1 DUF2575 family protein -
EFER_RS00345 17503..18444 + 942 WP_000767329.1 bifunctional riboflavin kinase/FAD synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T23297 WP_000809168.1 NC_011740:c14141-13989 [Escherichia fergusonii ATCC 35469]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T23297 NC_011740:c14141-13989 [Escherichia fergusonii ATCC 35469]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT23297 NC_011740:14190-14247 [Escherichia fergusonii ATCC 35469]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References