Detailed information of TA system TA232967

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2715365..2715585
• Replicon: chromosome
• Accession: NZ_CP091231
• Organism: Enterococcus faecalis strain 732

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: LQ055_RS13475
• Protein ID: WP_021164441.1
• Coordinates: 2715484..2715585 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2715365..2715539 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ055_RS13450	2711012..2711965	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
LQ055_RS13455	2712004..2712759	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
LQ055_RS13460	2712756..2713721	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
LQ055_RS13465	2713718..2714665	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
LQ055_RS13470	2714850..2715302	+	453	WP_002389410.1	YueI family protein	-
-	2715365..2715539	+	175	-	-	Antitoxin
LQ055_RS13475	2715484..2715585	-	102	WP_021164441.1	putative holin-like toxin	Toxin
LQ055_RS13480	2715917..2716018	-	102	WP_075551663.1	putative holin-like toxin	-
LQ055_RS13485	2716208..2718478	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
LQ055_RS13490	2718649..2719149	+	501	WP_002372831.1	cysteine hydrolase family protein	-
LQ055_RS13495	2719548..2720444	+	897	WP_002389477.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T232967 WP_021164441.1 NZ_CP091231:c2715585-2715484 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

>T232967 NZ_CP128506:c158965-158684 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAAGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin

Nucleotide

• Length: 175 bp

>AT232967 NZ_CP091231:2715365-2715539 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTATTTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAA
TCAGTAGTGCAACAA

Structures

Antitoxin