Detailed information of TA system TA232943

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2671516..2671799
• Replicon: chromosome
• Accession: NZ_CP091227
• Organism: Enterococcus faecalis strain 661

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: LQ066_RS12860
• Protein ID: WP_002411240.1
• Coordinates: 2671516..2671665 (+)
• Length: 50 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2671598..2671799 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ066_RS12845	2667173..2667805	-	633	WP_002358972.1	RloB family protein	-
LQ066_RS12850	2667814..2669109	-	1296	WP_002410675.1	ATP-binding protein	-
LQ066_RS12855	2669571..2671187	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
LQ066_RS12860	2671516..2671665	+	150	WP_002411240.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2671598..2671799	-	202	-	-	Antitoxin
LQ066_RS12865	2671896..2672039	+	144	WP_002396786.1	putative holin-like toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (16-49)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5738.05 Da
• Isoelectric Point: 11.3858

>T232943 WP_002411240.1 NZ_CP091227:2671516-2671665 [Enterococcus faecalis]
MRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 150 bp

>T232943 NZ_CP128492:1068440-1068706 [Novosphingobium resinovorum]
ATGGAAGTGCTCCCGTTCTCCGAAGCGCGCGCCAATTTCAAGGCGCTGATGGATCATGTGGTGGACGATCGTTCACCCGT
CATCGTTACACGCCAAAAGGCGGAAGCGGTGGTCGTGGTCTCGCTGTCCGACTGGAACGCAATGGCCGAAACCATGCACC
TTGTCTCGACCCCGGCGAATTCGACCCGCCTGCGCGATTCCGTTCGGGAACTCGATGGGGGGAAGGGCAGGAACGCAATC
TCGTCCAGCCATAGGAGGCTGGAGTGA

Antitoxin

Nucleotide

• Length: 202 bp

>AT232943 NZ_CP091227:c2671799-2671598 [Enterococcus faecalis]
GTTTTTTTAGGTAATTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTA
AGACGGTGACCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCA
ATTTCACAATCAGCGCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin