Detailed information of TA system TA232907

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 1672757..1672951
• Replicon: chromosome
• Accession: NZ_CP091198
• Organism: Enterococcus faecalis strain UK045

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L2629_RS08945
• Protein ID: WP_015543884.1
• Coordinates: 1672856..1672951 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1672757..1672821 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2629_RS08930	1668390..1670132	+	1743	WP_002399652.1	PTS transporter subunit EIIC	-
L2629_RS08935	1670123..1672156	+	2034	WP_002387671.1	PRD domain-containing protein	-
L2629_RS08940	1672167..1672601	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	1672757..1672821	+	65	-	-	Antitoxin
L2629_RS08945	1672856..1672951	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
L2629_RS08950	1673197..1674969	+	1773	WP_010706745.1	PTS mannitol-specific transporter subunit IIBC	-
L2629_RS08955	1674984..1675421	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
L2629_RS08960	1675436..1676590	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
L2629_RS08965	1676657..1677772	-	1116	WP_002379062.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T232907 WP_015543884.1 NZ_CP091198:c1672951-1672856 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T232907 NZ_CP128464:c2679013-2678870 [Enterococcus faecalis]
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAGACAATTCAGACGATCCTAGGTTTTGG
TATGTTTACCATTGCTTTGATTGCACTGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT232907 NZ_CP091198:1672757-1672821 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin