Detailed information of TA system TA232900

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1178266..1178662
• Replicon: chromosome
• Accession: NZ_CP091198
• Organism: Enterococcus faecalis strain UK045

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: Q82Z30
• Locus tag: L2629_RS06355
• Protein ID: WP_002387585.1
• Coordinates: 1178519..1178662 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1178266..1178408 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5244.37 Da
• Isoelectric Point: 10.5719

>T232900 WP_002387585.1 NZ_CP091198:1178519-1178662 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILKVVKEDKKK

Nucleotide

• Length: 144 bp

>T232900 NZ_CP128463:c36268-36011 [Enterococcus faecalis]
ATGGCGAATATTACTGACTTCACCGAAAAGCAATTTGAAGATCGTTTAGAAAAGAATGTTGAACGACTAACTAAAAATAG
ACTAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACGGTTCTGTTGCAAAGTTTTAAATCTACTA
TCAAATAAGGTAGAATAA

Antitoxin

Nucleotide

• Length: 143 bp

>AT232900 NZ_CP091198:c1178408-1178266 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCTTT
TTAGTTACAAAAAATAACCGTACTCAGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAA

Structures

Toxin

• AlphaFold DB: A0A059MXV6

Antitoxin