Detailed information of TA system TA232892

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1173543..1173975
• Replicon: chromosome
• Accession: NZ_CP091198
• Organism: Enterococcus faecalis strain UK045

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: L2629_RS06345
• Protein ID: WP_021164545.1
• Coordinates: 1173871..1173975 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1173543..1173719 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L2629_RS06330	1169255..1169887	-	633	WP_002358972.1	RloB family protein	-
L2629_RS06335	1169896..1171191	-	1296	WP_002379013.1	ATP-binding protein	-
L2629_RS17870	1171217..1171351	-	135	WP_002387582.1	hypothetical protein	-
L2629_RS06340	1171653..1173269	+	1617	WP_002379014.1	phosphatase PAP2/LCP family protein	-
-	1173543..1173719	-	177	-	-	Antitoxin
L2629_RS06345	1173871..1173975	+	105	WP_021164545.1	putative holin-like toxin	Toxin
L2629_RS06350	1174165..1177923	-	3759	WP_010706868.1	WxL domain-containing protein	-
L2629_RS06355	1178519..1178662	+	144	WP_002387585.1	putative holin-like toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T232892 WP_021164545.1 NZ_CP091198:1173871-1173975 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

>T232892 NZ_CP128454:232204-232554 [Geobacillus stearothermophilus]
TTGATTGTCAAACGTGGCGACGTGTATTTTGCGGATCTTTCCCCGGTTGTTGGCTCAGAGCAGGGCGGCGTCCGCCCCGT
GTTGGTGATCCAAAACGATATCGGCAATCGCTTCAGTCCAACGGTTATTGTAGCGGCGATCACGGCGCAAATCCAAAAGG
CAAAGCTGCCGACGCATGTCGAGATCGATGCGAAGCGCTACGGGTTTGAGCGGGACTCGGTCATTTTGCTTGAACAAATC
CGTACGATTGATAAGCAGCGGCTGACTGACAAAATCACCCATCTGGATGATGAGATGATGGACAAAGTCGATGAAGCGCT
GCAAATCAGCTTAGGGCTGATCGACTTTTGA

Antitoxin

Nucleotide

• Length: 177 bp

>AT232892 NZ_CP091198:c1173719-1173543 [Enterococcus faecalis]
TGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGACGGTGACCTTTT
GGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAACAGCTTTTAGGATTCCG
AAGATTAACGTTGCGAT

Structures

Antitoxin