Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3523885..3524495 Replicon chromosome
Accession NZ_CP091174
Organism Stutzerimonas stutzeri strain XX1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag L1776_RS16365 Protein ID WP_236450760.1
Coordinates 3524181..3524495 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag L1776_RS16360 Protein ID WP_058078068.1
Coordinates 3523885..3524175 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1776_RS16330 3519058..3519267 + 210 WP_003282211.1 cold-shock protein -
L1776_RS16335 3519372..3520466 - 1095 WP_011912443.1 iron-sulfur cluster carrier protein ApbC -
L1776_RS16340 3520638..3522677 + 2040 WP_084904908.1 methionine--tRNA ligase -
L1776_RS16345 3522735..3522941 + 207 WP_236450759.1 cysteine-rich CWC family protein -
L1776_RS16350 3522941..3523633 + 693 WP_108241596.1 16S rRNA pseudouridine(516) synthase -
L1776_RS16360 3523885..3524175 - 291 WP_058078068.1 NadS family protein Antitoxin
L1776_RS16365 3524181..3524495 - 315 WP_236450760.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L1776_RS16370 3524539..3525546 - 1008 WP_236450761.1 tyrosine-type recombinase/integrase -
L1776_RS16375 3525546..3526823 - 1278 WP_236450762.1 hypothetical protein -
L1776_RS16380 3526968..3528155 - 1188 WP_236450763.1 zonular occludens toxin domain-containing protein -
L1776_RS16385 3528168..3528494 - 327 WP_236450764.1 DUF2523 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12022.81 Da        Isoelectric Point: 9.8035

>T232869 WP_236450760.1 NZ_CP091174:c3524495-3524181 [Stutzerimonas stutzeri]
MIFIETPVFTKRLRELLNDDSYAEFQRQLAERPEMGDVIEGTGGIRKVRVATSGHGKRGGSRVIYYHFTAASQIALLLIY
PKNEKDDLTADERKVLKQIIERWR

Download         Length: 315 bp

>T232869 NZ_CP128416:c764457-764053 [Rhizobium sp. CSC1952]
ATGCCGTTGGTAGCGAATTTTCTCGATACGAACATACTTGTCTATGCGTTCAGCGAGGGCCCGAAAGCTGAGGTCGCTCA
AGCACTGATGGCAGAGCCGTTTGTGCTCAGCGTGCAGGCGCTCAACGAATTCGCAAATGTTGGGCGGAAGAAGCTGAAAT
TAAGCTGGGAGCGTATTGAGGAGGCGATTGATGACCTCTCTTCAGTGGCTTCCGCGATCGTCGTTTTGGATAAGCAGGCA
ACCAAAGCCGCTTTAAAGCTGGTCGGACGATACAACTTGGCTTTCTATGATGCTCTAATGTTGGCTGCTGCGTTGAAAGC
GAATTGCGGCCGATATTATTCCGAAGATCTCCAACATGGACTTTTGATCGACGGGAAGCTGACAGCTATAAATCCATTCC
GCTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10911.48 Da        Isoelectric Point: 8.8068

>AT232869 WP_058078068.1 NZ_CP091174:c3524175-3523885 [Stutzerimonas stutzeri]
MSKFFEDLLESVQQMDEIHRGERQPSREFTVDALQVKEIRKATGLTQAKFAAMIDVQLGTLRNWEQGRREPTGPAKALLR
AIHNDPKHVIQALSSV

Download         Length: 291 bp

>AT232869 NZ_CP128416:c764687-764457 [Rhizobium sp. CSC1952]
ATGCTGATCGCAAAATGGGGAAATAGTCTGGCAGTCCGTATTCCCGCGTCCGTCGTGGAAGCCTTGGACCTGAAGGAAGG
TGACGATATCGCTATTCGCGTTGCAGATGGTCCCGTCTTCGAAATCAAGCGGAACGATGTCCGCCAGAAGGCGCTTGAAC
GGATCAAGGCCTTTAAATTGAAGCTGCCGCCCGACTGGAAATTCGACCGCGACGAAGCGAACTCCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References