Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 266464..266972 Replicon chromosome
Accession NZ_CP091087
Organism Corynebacterium pseudodiphtheriticum strain CD1121

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag L2D23_RS01150 Protein ID WP_249624907.1
Coordinates 266464..266724 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L2D23_RS01155 Protein ID WP_249620205.1
Coordinates 266721..266972 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2D23_RS01135 (L2D23_01135) 261862..262581 - 720 WP_249624904.1 TetR/AcrR family transcriptional regulator -
L2D23_RS01140 (L2D23_01140) 262578..264122 - 1545 WP_249624905.1 MFS transporter -
L2D23_RS01145 (L2D23_01145) 264437..266467 + 2031 WP_249624906.1 BCCT family transporter -
L2D23_RS01150 (L2D23_01150) 266464..266724 - 261 WP_249624907.1 Txe/YoeB family addiction module toxin Toxin
L2D23_RS01155 (L2D23_01155) 266721..266972 - 252 WP_249620205.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L2D23_RS01160 (L2D23_01160) 267055..268125 + 1071 WP_249625316.1 hypothetical protein -
L2D23_RS01165 (L2D23_01165) 268153..269514 - 1362 WP_249624908.1 MFS transporter -
L2D23_RS01170 (L2D23_01170) 269654..270694 + 1041 WP_249624909.1 hypothetical protein -
L2D23_RS01175 (L2D23_01175) 270848..271579 - 732 WP_249624910.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10511.00 Da        Isoelectric Point: 10.3351

>T232713 WP_249624907.1 NZ_CP091087:c266724-266464 [Corynebacterium pseudodiphtheriticum]
MKLVWTESAWEDYTWWQTEDRKVLKRINRLIKEIQRNGNSGIGKPEPLKHGFQGYWSRRITDEHRIVYKIFGNELRIASC
RYHYGR

Download         Length: 261 bp

>T232713 NZ_CP128168:383687-384037 [Halobacillus sp. ACCC02827]
GTGATAGTCAAACGAGGAGACGTTTATTTCGCTGATTTGTCCCCGGTCGTGGGATCCGAACAAGGCGGGGTTCGTCCTGT
ACTCATCCTCCAAAATGATATTGGTAATCGTTTTAGCCCTACGGTAATCGTCGCCGCGATTACTGCGCAAATACAAAAAG
CCAAACTCCCTACACACGTAGAAATTAACGCAGAAAAATACGGGTTCGAACGAAACTCTGTGATCCTATTGGAACAAATC
AGAACGATTGATAAACAGCGTTTGACCGACAAGATTACTCAACTGGATGAACCGATGATGCAGCAAGTGAACAAATCCTT
GCAGATCAGTCTCGGTTTGATCGATTTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9386.46 Da        Isoelectric Point: 4.3016

>AT232713 WP_249620205.1 NZ_CP091087:c266972-266721 [Corynebacterium pseudodiphtheriticum]
MKTMSYSDSRAHYAEMLDTVTDDREEVIITRAGHEPVVVVSLDDYESLKETAYLLKSPANARRLLASIEQLENGEGTQRD
LLE

Download         Length: 252 bp

>AT232713 NZ_CP128168:383400-383681 [Halobacillus sp. ACCC02827]
ATGGTTTTGTCCGATAGCATGCAGGAGATTGTCATCCGGATTCCGGATAACCTACTCAATGAAGTGGATGGCTTCATTCA
ACTCGAAAACAGTGATCGGAGCGATTTCATGTGTCAAGCAACGAAAATGTATTTGCGTGAAAAGAAACAGCGTCATATAA
GAGAATCCATGCGTAGAGGCTACATGGAAATGGCGAAAATCAATCTCAACATCGCTTCAGAAGCGTTCCAAGCTGAAGAG
GAGGCAGACCACACCCTGGAGCAATTAGTGAGCGGGGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References