Detailed information of TA system TA232692

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 1848628..1849217
• Replicon: chromosome
• Accession: NZ_CP091075
• Organism: Xanthomonas arboricola pv. pruni strain T1

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A2S7AZR2
• Locus tag: K9U02_RS07910
• Protein ID: WP_039429225.1
• Coordinates: 1848936..1849217 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: K9U02_RS07905
• Protein ID: WP_006449989.1
• Coordinates: 1848628..1848918 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K9U02_RS07885 (K9U02_07885)	1844770..1845606	+	837	WP_081327584.1	restriction endonuclease	-
K9U02_RS07890 (K9U02_07890)	1845681..1847579	+	1899	WP_126750750.1	hypothetical protein	-
K9U02_RS07895 (K9U02_07895)	1847753..1848085	+	333	WP_039513672.1	lipoprotein	-
K9U02_RS07900 (K9U02_07900)	1848235..1848437	+	203	Protein_1547	hypothetical protein	-
K9U02_RS07905 (K9U02_07905)	1848628..1848918	-	291	WP_006449989.1	HigA family addiction module antitoxin	Antitoxin
K9U02_RS07910 (K9U02_07910)	1848936..1849217	-	282	WP_039429225.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K9U02_RS07915 (K9U02_07915)	1849357..1851483	-	2127	WP_043087609.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Toxin-antitoxin system, antidote protein, HigA (6-82)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11046.72 Da
• Isoelectric Point: 9.7972

>T232692 WP_039429225.1 NZ_CP091075:c1849217-1848936 [Xanthomonas arboricola pv. pruni]
MIRSFVDKEAEKIWLGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQWRICFRWM
EGDVAEVEIVDYH

Nucleotide

• Length: 282 bp

>T232692 NZ_CP127882:c104905-104618 [Serratia marcescens]
GTGATGTATACGATCAAATTTCGTGAGTCGGCTCTGAAAGAATGGGGCAAGCTGGACAAAGCGCTGCAGCAGCAGTTCGC
CAAAAAACTGAAAAAATGCTGCGAGAATCCGCATATTCCGTCAGCAAAACTGCGGGGGATGCCGGGGTGTTACAAGATCA
AGCTACGCGCCTCGGGGTTTCGTCTGGTTTATGAAGTGATCGACGATTGCCTGATTATCGCGGTGGTTGCCGTCGGTAAA
CGTGAGCGCGGGGATGTTTACCAGTTGGCCAGTGAGCGTCTTAAATAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10540.20 Da
• Isoelectric Point: 6.4664

>AT232692 WP_006449989.1 NZ_CP091075:c1848918-1848628 [Xanthomonas arboricola pv. pruni]
MTVLPNIHPGEILLEEFLEPMGISQNALARATDVPPRRINEIVLGKRGITADTAVRLAAALGTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Nucleotide

• Length: 291 bp

>AT232692 NZ_CP127882:c105153-104902 [Serratia marcescens]
ATGCCAAATATCATTCTGAGTGACACAAGTGCGAGCATCAGCGAGCTGAAGAAAAACCCAATGGAAACCGTTGGCGCCGG
TGACGGTTTTCCGGTGGCCATCCTGAACCGTAATCAGCCAGCATTTTATTGTGTGCCTGCGGCGCTCTATGAGCAAATGC
TCGATGCCATCGATGATCAGGAGCTGGTGAGATTGGTCAATGAGCGCCGGAGCGAAGCGCTGGTTGATATCGATCTGGAT
CAGTTCGCGTGA

Structures

Toxin

• AlphaFold DB: A0A2S7AZR2