Detailed information of TA system TA232647

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1815659..1815839
• Replicon: chromosome
• Accession: NZ_CP091066
• Organism: Staphylococcus aureus strain UMCG579

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: L1O91_RS08605
• Protein ID: WP_001801861.1
• Coordinates: 1815659..1815754 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1815782..1815839 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L1O91_RS08580	1811060..1811686	+	627	WP_054190584.1	hypothetical protein	-
L1O91_RS08585	1811727..1812068	+	342	WP_054190585.1	DUF3969 family protein	-
L1O91_RS08590	1812169..1812741	+	573	WP_054190586.1	hypothetical protein	-
L1O91_RS08595	1813118..1813954	+	837	WP_054190587.1	ATP-binding cassette domain-containing protein	-
L1O91_RS08600	1814761..1815207	-	447	WP_054190589.1	DUF1433 domain-containing protein	-
L1O91_RS08605	1815659..1815754	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1815782..1815839	-	58	-	-	Antitoxin
L1O91_RS08610	1815877..1815978	+	102	WP_054190590.1	hypothetical protein	-
L1O91_RS08615	1815964..1816231	-	268	Protein_1692	transposase	-
L1O91_RS08620	1816263..1816625	+	363	WP_054190591.1	colicin E3/pyocin S6 family cytotoxin	-
L1O91_RS08625	1816647..1817150	+	504	WP_054190592.1	hypothetical protein	-
L1O91_RS08630	1817705..1818148	-	444	WP_054190593.1	DUF1433 domain-containing protein	-
L1O91_RS08635	1818148..1818591	-	444	WP_054190594.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T232647 WP_001801861.1 NZ_CP091066:1815659-1815754 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T232647 NZ_CP127850:68599-68904 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT232647 NZ_CP091066:c1815839-1815782 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin