Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3069271..3069783 Replicon chromosome
Accession NZ_CP091036
Organism Antarcticibacterium sp. 1MA-6-2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LZ575_RS15675 Protein ID WP_235325465.1
Coordinates 3069526..3069783 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LZ575_RS15670 Protein ID WP_235325463.1
Coordinates 3069271..3069525 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ575_RS15650 (LZ575_15650) 3064561..3066961 + 2401 Protein_3144 TonB-dependent receptor -
LZ575_RS15655 (LZ575_15655) 3067140..3067436 + 297 WP_235325457.1 type II toxin-antitoxin system HigB family toxin -
LZ575_RS15660 (LZ575_15660) 3067448..3067816 + 369 WP_235325459.1 transcriptional regulator -
LZ575_RS15665 (LZ575_15665) 3067970..3068680 + 711 WP_235325461.1 hypothetical protein -
LZ575_RS15670 (LZ575_15670) 3069271..3069525 + 255 WP_235325463.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LZ575_RS15675 (LZ575_15675) 3069526..3069783 + 258 WP_235325465.1 Txe/YoeB family addiction module toxin Toxin
LZ575_RS15680 (LZ575_15680) 3070032..3070337 - 306 WP_235325467.1 hypothetical protein -
LZ575_RS15685 (LZ575_15685) 3070710..3071159 + 450 WP_235325469.1 GNAT family N-acetyltransferase -
LZ575_RS15690 (LZ575_15690) 3071227..3071373 + 147 WP_235325471.1 hypothetical protein -
LZ575_RS15695 (LZ575_15695) 3071425..3071772 + 348 WP_235325473.1 dihydrofolate reductase family protein -
LZ575_RS15700 (LZ575_15700) 3072336..3074414 + 2079 WP_235325475.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10503.09 Da        Isoelectric Point: 9.5407

>T232509 WP_235325465.1 NZ_CP091036:3069526-3069783 [Antarcticibacterium sp. 1MA-6-2]
MKYIFVDESWEDYLYWQKTDRKKLKKINELLKDIARNPFDGIGKPEPLKHKYAGFFSRRIDSEHRLIYQYREGEILIAKC
RFHYD

Download         Length: 258 bp

>T232509 NZ_CP127314:c2330189-2329815 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTACGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9621.02 Da        Isoelectric Point: 8.5283

>AT232509 WP_235325463.1 NZ_CP091036:3069271-3069525 [Antarcticibacterium sp. 1MA-6-2]
MQITTVSEFRKDIKTYLDRVVKNFETLIINRGKDSGIVVMSLQEYNSLMATNHELSSRKNELRLDSAIEKLKSGAAFNKD
LIEN

Download         Length: 255 bp

>AT232509 NZ_CP127314:c2330646-2330278 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGTTGCTGATGAAACAACTGGAGCTCATGCTCACCAGTGGT
GAACTCAGCCCCCGCTATCAGCATACCGTCACGCTGTATGCGAAAGGACTGACCTGCGAAGCCGATACCCTGGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References