Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3037029..3037731 Replicon chromosome
Accession NC_011420
Organism Rhodospirillum centenum SW (Rhodocista centenaria SW)

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag RC1_RS14140 Protein ID WP_041786558.1
Coordinates 3037029..3037388 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag RC1_RS14145 Protein ID WP_148213463.1
Coordinates 3037411..3037731 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RC1_RS20880 3032930..3033880 - 951 WP_184446341.1 reverse transcriptase family protein -
RC1_RS20885 3033843..3034190 - 348 WP_085979019.1 helix-turn-helix transcriptional regulator -
RC1_RS14130 3034826..3035518 - 693 WP_148213582.1 nucleotide exchange factor GrpE -
RC1_RS14135 3035661..3036698 - 1038 WP_012568105.1 heat-inducible transcriptional repressor HrcA -
RC1_RS14140 3037029..3037388 + 360 WP_041786558.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RC1_RS14145 3037411..3037731 + 321 WP_148213463.1 XRE family transcriptional regulator Antitoxin
RC1_RS14150 3037789..3038508 + 720 WP_012568108.1 ribonuclease PH -
RC1_RS14155 3038505..3039116 + 612 WP_012568109.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
RC1_RS14160 3039592..3040317 + 726 WP_012568110.1 SIMPL domain-containing protein -
RC1_RS14165 3040416..3041579 + 1164 WP_012568111.1 coproporphyrinogen III oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-108)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13490.49 Da        Isoelectric Point: 10.3044

>T23228 WP_041786558.1 NC_011420:3037029-3037388 [Rhodospirillum centenum SW]
MPWTVLFHPEFWPEFLDLRAPVQDELAARMKRLQATGPLTGRPDVDTLKGSSFANMKELRFSVDGGVWRVAFAFDPDKQA
VLLVAGDKAGVAQDRFYRTLIRKADERYARHLQAGRTKG

Download         Length: 360 bp

>T23228 NC_011420:3037029-3037388 [Rhodospirillum centenum SW]
ATGCCCTGGACCGTTCTGTTCCATCCTGAGTTCTGGCCGGAGTTTCTGGACCTCCGGGCTCCGGTGCAGGACGAACTGGC
GGCCAGGATGAAGCGGCTTCAGGCGACCGGCCCCCTGACGGGCAGGCCGGACGTGGACACCCTGAAGGGGTCTTCGTTCG
CGAACATGAAGGAACTCCGCTTCAGTGTGGATGGCGGGGTCTGGCGGGTTGCCTTCGCGTTCGACCCGGACAAGCAGGCG
GTCCTGCTTGTCGCGGGCGACAAGGCGGGTGTGGCCCAGGACAGATTCTATCGCACGCTGATCCGGAAGGCGGACGAGCG
TTACGCCCGCCACCTGCAAGCCGGACGGACCAAGGGCTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11821.46 Da        Isoelectric Point: 4.7187

>AT23228 WP_148213463.1 NC_011420:3037411-3037731 [Rhodospirillum centenum SW]
MSGTRTLDDWLASLPPDRRERIEARADALEAEELTLQGLRKALDLTQAKIAESLDVRQDTVSRIERQTDMLLSTLSGYVE
AMGGRLELTVRFPGRPPVRITGLSDL

Download         Length: 321 bp

>AT23228 NC_011420:3037411-3037731 [Rhodospirillum centenum SW]
ATGAGCGGAACCAGGACGCTGGACGATTGGCTCGCTTCCCTGCCGCCCGACCGGCGGGAGCGGATCGAGGCCAGGGCGGA
CGCGCTGGAGGCGGAGGAACTGACCCTCCAGGGTCTGCGCAAGGCGCTCGACCTGACGCAGGCGAAGATCGCGGAAAGCC
TGGACGTGCGGCAGGACACGGTGTCGCGCATCGAGCGCCAGACGGACATGCTGCTGTCCACCCTGTCCGGCTATGTCGAA
GCCATGGGGGGCCGGCTGGAACTGACGGTCCGTTTCCCCGGCCGGCCGCCGGTCCGGATCACGGGGCTTTCGGACTTGTA
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References