Detailed information of TA system TA232006

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1693057..1693241
• Replicon: chromosome
• Accession: NZ_CP090877
• Organism: Staphylococcus aureus strain SAUR_BFS11

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: L1A06_RS08160
• Protein ID: WP_000482647.1
• Coordinates: 1693057..1693164 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1693181..1693241 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L1A06_RS08135	1688429..1688902	+	474	WP_000456492.1	GyrI-like domain-containing protein	-
L1A06_RS08140	1689025..1690236	-	1212	WP_103150279.1	multidrug effflux MFS transporter	-
L1A06_RS08145	1690418..1691077	-	660	WP_000831295.1	hypothetical protein	-
L1A06_RS08150	1691137..1692279	-	1143	WP_001176863.1	glycerate kinase	-
L1A06_RS08155	1692537..1692923	+	387	WP_000779360.1	flippase GtxA	-
L1A06_RS08160	1693057..1693164	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1693181..1693241	-	61	-	-	Antitoxin
L1A06_RS08165	1693868..1695631	+	1764	WP_001064836.1	ABC transporter ATP-binding protein	-
L1A06_RS08170	1695656..1697389	+	1734	WP_000486496.1	ABC transporter ATP-binding protein	-
L1A06_RS08175	1697620..1697787	+	168	WP_001792506.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T232006 WP_000482647.1 NZ_CP090877:1693057-1693164 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T232006 NZ_CP127153:c5424364-5423981 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT232006 NZ_CP090877:c1693241-1693181 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin