Detailed information of TA system TA231996

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 456629..456809
• Replicon: chromosome
• Accession: NZ_CP090876
• Organism: Staphylococcus aureus strain SAUR_BFS12

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: L0998_RS02625
• Protein ID: WP_001801861.1
• Coordinates: 456714..456809 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	456629..456686 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0998_RS02595	453877..454320	+	444	WP_054190594.1	DUF1433 domain-containing protein	-
L0998_RS02600	454320..454763	+	444	WP_054190593.1	DUF1433 domain-containing protein	-
L0998_RS02605	455318..455821	-	504	WP_054190592.1	hypothetical protein	-
L0998_RS02610	455843..456205	-	363	WP_054190591.1	colicin E3/pyocin S6 family cytotoxin	-
L0998_RS02615	456237..456504	+	268	Protein_471	transposase	-
L0998_RS02620	456490..456591	-	102	WP_054190590.1	hypothetical protein	-
-	456629..456686	+	58	-	-	Antitoxin
L0998_RS02625	456714..456809	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
L0998_RS02630	457261..457707	+	447	WP_054190589.1	DUF1433 domain-containing protein	-
L0998_RS02635	458514..459350	-	837	WP_054190587.1	ATP-binding cassette domain-containing protein	-
L0998_RS02640	459727..460299	-	573	WP_054190586.1	hypothetical protein	-
L0998_RS02645	460400..460741	-	342	WP_054190585.1	DUF3969 family protein	-
L0998_RS02650	460782..461408	-	627	WP_054190584.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T231996 WP_001801861.1 NZ_CP090876:c456809-456714 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T231996 NZ_CP127153:327489-327857 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT231996 NZ_CP090876:456629-456686 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin