231842

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1174430..1175129 Replicon chromosome
Accession NZ_CP090765
Organism Burkholderia multivorans strain 2008Ycf542

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L0Y85_RS04965 Protein ID WP_105836523.1
Coordinates 1174833..1175129 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag L0Y85_RS04960 Protein ID WP_105836522.1
Coordinates 1174430..1174831 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y85_RS04940 (L0Y85_04940) 1170133..1171485 - 1353 WP_006413139.1 LLM class flavin-dependent oxidoreductase -
L0Y85_RS04945 (L0Y85_04945) 1171482..1172543 - 1062 WP_105836521.1 LLM class flavin-dependent oxidoreductase -
L0Y85_RS04950 (L0Y85_04950) 1172574..1173515 - 942 WP_039217954.1 ABC transporter substrate-binding protein -
L0Y85_RS04955 (L0Y85_04955) 1173581..1174141 - 561 WP_059786242.1 GNAT family N-acetyltransferase -
L0Y85_RS04960 (L0Y85_04960) 1174430..1174831 - 402 WP_105836522.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L0Y85_RS04965 (L0Y85_04965) 1174833..1175129 - 297 WP_105836523.1 type II toxin-antitoxin system MqsR family toxin Toxin
L0Y85_RS04970 (L0Y85_04970) 1175249..1176283 - 1035 WP_105836524.1 succinylglutamate desuccinylase/aspartoacylase family protein -
L0Y85_RS04975 (L0Y85_04975) 1176386..1176658 - 273 WP_105836525.1 hypothetical protein -
L0Y85_RS04980 (L0Y85_04980) 1176866..1178410 - 1545 WP_175848070.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11213.13 Da        Isoelectric Point: 9.1122

>T231842 WP_105836523.1 NZ_CP090765:c1175129-1174833 [Burkholderia multivorans]
MEKRTPHCKLPRVKALIEAGKVRLTASAVIGARQMGFTEAETIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T231842 NZ_CP126962:2243920-2244120 [Globicatella sanguinis]
ATGCCTTTGACGCAATTAGAGATGATGAAATTGTTGATGTTGCATGGATGGACACCCTATACCAGAGAGGGGAAAGGCTC
CCATATAAAAATGAAAAAGAAAGGATGCCGACCAATTATCATTCCACATGGAGAATTAAAAAGAGGTACAGAACGCAATA
TATTAAAACAGGCCAATTTATTGGCATTATGGCATCATTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14419.59 Da        Isoelectric Point: 7.6703

>AT231842 WP_105836522.1 NZ_CP090765:c1174831-1174430 [Burkholderia multivorans]
MKCPACGAAALVRDTRDIPYTYKGESTVIPHVTGEFCPACGESVLDVGEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLDEVRAA

Download         Length: 402 bp

>AT231842 NZ_CP126962:2244136-2244582 [Globicatella sanguinis]
ATGCAAGTAGTTTATCCCGCTTTATTTTATTTTGATCCAAAGGAGAGCAATTATTTTATTACATTTCCTGACTTTGAATA
TTCTGCTACTCAAGGCGAAAATCTTGCGGATGCGATGATGATGGCCGCCGAGTATTTGGGGATACAAGTAGCCGATTTGA
TTGAAGAGAATCACACATTGCCTATCCCAACTAATATAAATGAGTTATCATTAATTGAACACAATCCATTTAGAGAAGAT
TCGGAGTTTAGTCAAGATTACGATGAACAGCAATCATTTATTTCAATGGTTACTACAGATGTCACTCGATATCTAGGTAT
GCAAGAGTTAGTAAAAAAAACACTCACAATCCCTAAATGGGCTGATATCGCTGGGAAAGAATTGCAATTAAACTTCTCTC
AAACTTTAACAGAAGCGATATTAGCGAAGAAGTTTGAATCATCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References