Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1272694..1273393 Replicon chromosome
Accession NZ_CP090727
Organism Burkholderia multivorans strain 2014Y70439247

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L0Z30_RS05845 Protein ID WP_105751843.1
Coordinates 1272694..1272990 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID B9BI88
Locus tag L0Z30_RS05850 Protein ID WP_006403504.1
Coordinates 1272992..1273393 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Z30_RS05830 (L0Z30_05830) 1269419..1270960 + 1542 WP_167338149.1 sensor domain-containing diguanylate cyclase -
L0Z30_RS05835 (L0Z30_05835) 1271167..1271439 + 273 WP_006403506.1 hypothetical protein -
L0Z30_RS05840 (L0Z30_05840) 1271540..1272574 + 1035 WP_069221065.1 succinylglutamate desuccinylase/aspartoacylase family protein -
L0Z30_RS05845 (L0Z30_05845) 1272694..1272990 + 297 WP_105751843.1 type II toxin-antitoxin system MqsR family toxin Toxin
L0Z30_RS05850 (L0Z30_05850) 1272992..1273393 + 402 WP_006403504.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L0Z30_RS05855 (L0Z30_05855) 1273682..1274242 + 561 WP_105751842.1 GNAT family N-acetyltransferase -
L0Z30_RS05860 (L0Z30_05860) 1274308..1275249 + 942 WP_035487669.1 ABC transporter substrate-binding protein -
L0Z30_RS05865 (L0Z30_05865) 1275281..1276342 + 1062 WP_105751841.1 LLM class flavin-dependent oxidoreductase -
L0Z30_RS05870 (L0Z30_05870) 1276339..1277691 + 1353 WP_006409061.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11128.07 Da        Isoelectric Point: 9.1122

>T231731 WP_105751843.1 NZ_CP090727:1272694-1272990 [Burkholderia multivorans]
MEKRTAHCKLPRVKALIEAGKVRLTASAVIGARLMGFTEAEAIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T231731 NZ_CP126946:c1835886-1835779 [Escherichia coli O78:H51]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGACGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14521.68 Da        Isoelectric Point: 7.0834

>AT231731 WP_006403504.1 NZ_CP090727:1272992-1273393 [Burkholderia multivorans]
MKCPACGAATLVRDTRDIPYTYKGESTVIPHITGEFCPACGESVLDVDEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKILDRHPDLLDEVRAA

Download         Length: 402 bp

>AT231731 NZ_CP126946:1835933-1835999 [Escherichia coli O78:H51]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B9BI88

References