Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1188871..1189570 Replicon chromosome
Accession NZ_CP090717
Organism Burkholderia multivorans strain 2014Y70532416II

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L0Y81_RS05035 Protein ID WP_105836523.1
Coordinates 1189274..1189570 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag L0Y81_RS05030 Protein ID WP_105836522.1
Coordinates 1188871..1189272 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y81_RS05010 (L0Y81_05010) 1184574..1185926 - 1353 WP_006413139.1 LLM class flavin-dependent oxidoreductase -
L0Y81_RS05015 (L0Y81_05015) 1185923..1186984 - 1062 WP_105836521.1 LLM class flavin-dependent oxidoreductase -
L0Y81_RS05020 (L0Y81_05020) 1187015..1187956 - 942 WP_039217954.1 ABC transporter substrate-binding protein -
L0Y81_RS05025 (L0Y81_05025) 1188022..1188582 - 561 WP_059786242.1 GNAT family N-acetyltransferase -
L0Y81_RS05030 (L0Y81_05030) 1188871..1189272 - 402 WP_105836522.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L0Y81_RS05035 (L0Y81_05035) 1189274..1189570 - 297 WP_105836523.1 type II toxin-antitoxin system MqsR family toxin Toxin
L0Y81_RS05040 (L0Y81_05040) 1189692..1190726 - 1035 WP_105836524.1 succinylglutamate desuccinylase/aspartoacylase family protein -
L0Y81_RS05045 (L0Y81_05045) 1190829..1191101 - 273 WP_105836525.1 hypothetical protein -
L0Y81_RS05050 (L0Y81_05050) 1191309..1192853 - 1545 WP_175848070.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11213.13 Da        Isoelectric Point: 9.1122

>T231707 WP_105836523.1 NZ_CP090717:c1189570-1189274 [Burkholderia multivorans]
MEKRTPHCKLPRVKALIEAGKVRLTASAVIGARQMGFTEAETIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T231707 NZ_CP126944:2895380-2895487 [Escherichia coli O1:K1:H7]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14419.59 Da        Isoelectric Point: 7.6703

>AT231707 WP_105836522.1 NZ_CP090717:c1189272-1188871 [Burkholderia multivorans]
MKCPACGAAALVRDTRDIPYTYKGESTVIPHVTGEFCPACGESVLDVGEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLDEVRAA

Download         Length: 402 bp

>AT231707 NZ_CP126944:c2895327-2895266 [Escherichia coli O1:K1:H7]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References