231679

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1200017..1200716 Replicon chromosome
Accession NZ_CP090705
Organism Burkholderia multivorans strain 2016Y70888756VI

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L0Z41_RS23895 Protein ID WP_105751843.1
Coordinates 1200017..1200313 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID B9BI88
Locus tag L0Z41_RS23900 Protein ID WP_006403504.1
Coordinates 1200315..1200716 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Z41_RS23880 (L0Z41_23880) 1196742..1198283 + 1542 WP_167338149.1 sensor domain-containing diguanylate cyclase -
L0Z41_RS23885 (L0Z41_23885) 1198490..1198762 + 273 WP_006403506.1 hypothetical protein -
L0Z41_RS23890 (L0Z41_23890) 1198863..1199897 + 1035 WP_069221065.1 succinylglutamate desuccinylase/aspartoacylase family protein -
L0Z41_RS23895 (L0Z41_23895) 1200017..1200313 + 297 WP_105751843.1 type II toxin-antitoxin system MqsR family toxin Toxin
L0Z41_RS23900 (L0Z41_23900) 1200315..1200716 + 402 WP_006403504.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L0Z41_RS23905 (L0Z41_23905) 1201005..1201565 + 561 WP_105751842.1 GNAT family N-acetyltransferase -
L0Z41_RS23910 (L0Z41_23910) 1201631..1202572 + 942 WP_035487669.1 ABC transporter substrate-binding protein -
L0Z41_RS23915 (L0Z41_23915) 1202604..1203665 + 1062 WP_105751841.1 LLM class flavin-dependent oxidoreductase -
L0Z41_RS23920 (L0Z41_23920) 1203662..1205014 + 1353 WP_006409061.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11128.07 Da        Isoelectric Point: 9.1122

>T231679 WP_105751843.1 NZ_CP090705:1200017-1200313 [Burkholderia multivorans]
MEKRTAHCKLPRVKALIEAGKVRLTASAVIGARLMGFTEAEAIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T231679 NZ_CP126942:2895270-2895377 [Escherichia coli O1:K1:H7]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14521.68 Da        Isoelectric Point: 7.0834

>AT231679 WP_006403504.1 NZ_CP090705:1200315-1200716 [Burkholderia multivorans]
MKCPACGAATLVRDTRDIPYTYKGESTVIPHITGEFCPACGESVLDVDEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKILDRHPDLLDEVRAA

Download         Length: 402 bp

>AT231679 NZ_CP126942:c2895217-2895156 [Escherichia coli O1:K1:H7]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B9BI88

References