231644

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1137017..1137716 Replicon chromosome
Accession NZ_CP090694
Organism Burkholderia multivorans strain 2017Y71079786

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag L0Y98_RS24810 Protein ID WP_059786235.1
Coordinates 1137420..1137716 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID B9B077
Locus tag L0Y98_RS24805 Protein ID WP_006397015.1
Coordinates 1137017..1137418 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y98_RS24785 (L0Y98_24785) 1132723..1134075 - 1353 WP_155825038.1 LLM class flavin-dependent oxidoreductase -
L0Y98_RS24790 (L0Y98_24790) 1134072..1135133 - 1062 WP_155825037.1 LLM class flavin-dependent oxidoreductase -
L0Y98_RS24795 (L0Y98_24795) 1135164..1136105 - 942 WP_155825036.1 ABC transporter substrate-binding protein -
L0Y98_RS24800 (L0Y98_24800) 1136171..1136731 - 561 WP_155825035.1 GNAT family N-acetyltransferase -
L0Y98_RS24805 (L0Y98_24805) 1137017..1137418 - 402 WP_006397015.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
L0Y98_RS24810 (L0Y98_24810) 1137420..1137716 - 297 WP_059786235.1 type II toxin-antitoxin system MqsR family toxin Toxin
L0Y98_RS24815 (L0Y98_24815) 1137836..1138870 - 1035 WP_006397017.1 succinylglutamate desuccinylase/aspartoacylase family protein -
L0Y98_RS24820 (L0Y98_24820) 1138973..1139245 - 273 WP_012216969.1 hypothetical protein -
L0Y98_RS24825 (L0Y98_24825) 1139453..1140997 - 1545 WP_170935331.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11215.10 Da        Isoelectric Point: 9.1122

>T231644 WP_059786235.1 NZ_CP090694:c1137716-1137420 [Burkholderia multivorans]
MEKRTPHCKLPRVKALIEAGKVRLTASAVIGARQMGFTESETIDVVRALTPFEFHKSMTTYADHTIWQDVYRPCTMRGDV
YLKLTVVDDVLIVSFKER

Download         Length: 297 bp

>T231644 NZ_CP126940:196981-197088 [Escherichia coli O2:K1:H7]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14477.62 Da        Isoelectric Point: 7.0834

>AT231644 WP_006397015.1 NZ_CP090694:c1137418-1137017 [Burkholderia multivorans]
MKCPACGAAALVRDTRDIPYTYKGESTVIPHVTGEFCPACGESVLDVDEATRFGEAVSAFNRQVNATLVDPKFIATVRKK
LKLDQREAAEIFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLDEVRAA

Download         Length: 402 bp

>AT231644 NZ_CP126940:c196924-196867 [Escherichia coli O2:K1:H7]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB B9B077

References