Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 140433..141133 Replicon chromosome
Accession NZ_CP090641
Organism Burkholderia contaminans strain LMG 23361

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1E3FT75
Locus tag LXE91_RS18395 Protein ID WP_039357707.1
Coordinates 140433..140729 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A4R4BTY4
Locus tag LXE91_RS18400 Protein ID WP_039357704.1
Coordinates 140732..141133 (+) Length 134 a.a.

Genomic Context

LXE91_RS18380LXE91_RS18385LXE91_RS18390LXE91_RS18395LXE91_RS18400LXE91_RS18405LXE91_RS18410LXE91_RS18415LXE91_RS18420
Location: 136958..138508 (1551 bp)
Type: Others
Protein ID: WP_039357717.1
Location: 138750..139034 (285 bp)
Type: Others
Protein ID: WP_039357714.1
Location: 139286..140329 (1044 bp)
Type: Others
Protein ID: WP_039357711.1
Location: 140433..140729 (297 bp)
Type: Toxin
Protein ID: WP_039357707.1
Location: 140732..141133 (402 bp)
Type: Antitoxin
Protein ID: WP_039357704.1
Location: 141452..142012 (561 bp)
Type: Others
Protein ID: WP_039357701.1
Location: 142069..143016 (948 bp)
Type: Others
Protein ID: WP_039357698.1
Location: 143069..144118 (1050 bp)
Type: Others
Protein ID: WP_039357696.1
Location: 144126..145478 (1353 bp)
Type: Others
Protein ID: WP_039357693.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LXE91_RS18380 (LXE91_18305)136958..138508+1551WP_039357717.1sensor domain-containing diguanylate cyclase-
LXE91_RS18385 (LXE91_18310)138750..139034+285WP_039357714.1hypothetical protein-
LXE91_RS18390 (LXE91_18315)139286..140329+1044WP_039357711.1succinylglutamate desuccinylase/aspartoacylase family protein-
LXE91_RS18395 (LXE91_18320)140433..140729+297WP_039357707.1type II toxin-antitoxin system MqsR family toxinToxin
LXE91_RS18400 (LXE91_18325)140732..141133+402WP_039357704.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
LXE91_RS18405 (LXE91_18330)141452..142012+561WP_039357701.1GNAT family N-acetyltransferase-
LXE91_RS18410 (LXE91_18335)142069..143016+948WP_039357698.1ABC transporter substrate-binding protein-
LXE91_RS18415 (LXE91_18340)143069..144118+1050WP_039357696.1LLM class flavin-dependent oxidoreductase-
LXE91_RS18420 (LXE91_18345)144126..145478+1353WP_039357693.1LLM class flavin-dependent oxidoreductase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11206.04 Da        Isoelectric Point: 8.0535

>T231552 WP_039357707.1 NZ_CP090641:140433-140729 [Burkholderia contaminans]
MEKRTPHCKLPRVKALVETGQVRLTASAVLGARLLGFTEREALDVVLSLTDLDFHKSMTTYADHTIWQDVYRPFTVRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T231552 NZ_CP126928:c2722074-2721972 [Escherichia coli O2:K1:H4]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14649.94 Da        Isoelectric Point: 8.8304

>AT231552 WP_039357704.1 NZ_CP090641:140732-141133 [Burkholderia contaminans]
MKCPACGAARLVRDTRDIPYTYKGRSTVVRDITGDFCPACGESVLDLDEATRLGEAITEFNKQVNATIVDPKYIAKVRKK
LKLDQREAAELFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLAEVRAA

Download         Length: 402 bp

>AT231552 NZ_CP126928:2721934-2722202 [Escherichia coli O2:K1:H4]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1E3FT75

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4R4BTY4

References