Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 288367..289067 Replicon chromosome
Accession NZ_CP090609
Organism Burkholderia cepacia strain CMCC(B)23005

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LZ568_RS19320 Protein ID WP_059697270.1
Coordinates 288771..289067 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LZ568_RS19315 Protein ID WP_059697271.1
Coordinates 288367..288768 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ568_RS19295 (LZ568_19295) 284001..285353 - 1353 WP_059697275.1 LLM class flavin-dependent oxidoreductase -
LZ568_RS19300 (LZ568_19300) 285361..286410 - 1050 WP_059697274.1 LLM class flavin-dependent oxidoreductase -
LZ568_RS19305 (LZ568_19305) 286479..287432 - 954 WP_059697273.1 ABC transporter substrate-binding protein -
LZ568_RS19310 (LZ568_19310) 287489..288049 - 561 WP_059697272.1 GNAT family N-acetyltransferase -
LZ568_RS19315 (LZ568_19315) 288367..288768 - 402 WP_059697271.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LZ568_RS19320 (LZ568_19320) 288771..289067 - 297 WP_059697270.1 type II toxin-antitoxin system MqsR family toxin Toxin
LZ568_RS19325 (LZ568_19325) 289171..290211 - 1041 WP_059697269.1 succinylglutamate desuccinylase/aspartoacylase family protein -
LZ568_RS19330 (LZ568_19330) 290466..290741 - 276 WP_027791638.1 hypothetical protein -
LZ568_RS19335 (LZ568_19335) 290985..292535 - 1551 WP_059697268.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11204.02 Da        Isoelectric Point: 8.9573

>T231404 WP_059697270.1 NZ_CP090609:c289067-288771 [Burkholderia cepacia]
MEKRRPHCKLTLVKALVESGQVRLTASAVLGARQLGFTEREALDVVMSLTDLDFHKSKTTYADHTIWQDVYRPLTVRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T231404 NZ_CP126345:c4588553-4588242 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTATTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14556.77 Da        Isoelectric Point: 8.4833

>AT231404 WP_059697271.1 NZ_CP090609:c288768-288367 [Burkholderia cepacia]
MKCPACGAAKLVRDTRDIPYTYKGRSTVVRAVTGEFCPACGESVLDLDEATRFGEAISEFNKQVNATIVDPNYIATVRKK
LKLDQREAAELFGGGVNAFSRYETGKTNPPLALVKLLKILDRHPDLLAEVRAA

Download         Length: 402 bp

>AT231404 NZ_CP126345:c4588241-4587951 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References