Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1795701..1796182 Replicon chromosome
Accession NZ_CP090598
Organism Bifidobacterium pseudocatenulatum strain JCLA3

Toxin (Protein)


Gene name yoeB Uniprot ID A0A0A7I4B7
Locus tag L0J99_RS07790 Protein ID WP_039199122.1
Coordinates 1795701..1795964 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L0J99_RS07795 Protein ID WP_234737409.1
Coordinates 1795964..1796182 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0J99_RS07775 (L0J99_07775) 1791439..1791831 - 393 WP_022244754.1 DNA mismatch endonuclease Vsr -
L0J99_RS07780 (L0J99_07780) 1792106..1793110 + 1005 WP_047749651.1 Gfo/Idh/MocA family oxidoreductase -
L0J99_RS07785 (L0J99_07785) 1793531..1795285 + 1755 WP_229031205.1 UvrD-helicase domain-containing protein -
L0J99_RS07790 (L0J99_07790) 1795701..1795964 - 264 WP_039199122.1 Txe/YoeB family addiction module toxin Toxin
L0J99_RS07795 (L0J99_07795) 1795964..1796182 - 219 WP_234737409.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L0J99_RS07800 (L0J99_07800) 1796640..1797662 + 1023 WP_234737410.1 DEAD/DEAH box helicase family protein -
L0J99_RS07805 (L0J99_07805) 1797662..1799035 + 1374 WP_234737411.1 DUF3427 domain-containing protein -
L0J99_RS07810 (L0J99_07810) 1799535..1799957 + 423 WP_033524377.1 hypothetical protein -
L0J99_RS07815 (L0J99_07815) 1800121..1800552 - 432 WP_004220939.1 PH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10153.51 Da        Isoelectric Point: 7.0093

>T231398 WP_039199122.1 NZ_CP090598:c1795964-1795701 [Bifidobacterium pseudocatenulatum]
VILSWTEDAWDDYLYWQRQDPKTFKRINLLIKDAMRSPAEGIGKPEPLKWALQGAWSRRIDSANRLVYTIDDDGITILSA
KSHYSKE

Download         Length: 264 bp

>T231398 NZ_CP126345:2715115-2715222 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8251.24 Da        Isoelectric Point: 4.4067

>AT231398 WP_234737409.1 NZ_CP090598:c1796182-1795964 [Bifidobacterium pseudocatenulatum]
MRKANEDADAILVTNSDPKDNVIVMSASDYDSLMETLHIYENPYLMDKVQRGLAQVKSRQTIRHDLIEQEGE

Download         Length: 219 bp

>AT231398 NZ_CP126345:c2715065-2715002 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A7I4B7

Antitoxin

Source ID Structure

References