Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 514991..515493 Replicon chromosome
Accession NZ_CP090596
Organism Pectobacterium aroidearum strain QJ003

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag L0Y20_RS02250 Protein ID WP_039282578.1
Coordinates 514991..515245 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag L0Y20_RS02255 Protein ID WP_039324900.1
Coordinates 515242..515493 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y20_RS02230 (L0Y20_02230) 510149..511411 - 1263 WP_181845053.1 L-rhamnose isomerase -
L0Y20_RS02235 (L0Y20_02235) 511408..512898 - 1491 WP_256599337.1 rhamnulokinase -
L0Y20_RS02240 (L0Y20_02240) 513234..514073 + 840 WP_180778897.1 HTH-type transcriptional activator RhaS -
L0Y20_RS02245 (L0Y20_02245) 514098..514952 + 855 WP_181845054.1 helix-turn-helix domain-containing protein -
L0Y20_RS02250 (L0Y20_02250) 514991..515245 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
L0Y20_RS02255 (L0Y20_02255) 515242..515493 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
L0Y20_RS02260 (L0Y20_02260) 515569..517278 - 1710 WP_256599338.1 ABC transporter ATP-binding protein -
L0Y20_RS02265 (L0Y20_02265) 517275..518141 - 867 WP_010285293.1 ABC transporter permease -
L0Y20_RS02270 (L0Y20_02270) 518134..519093 - 960 WP_256599339.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T231380 WP_039282578.1 NZ_CP090596:c515245-514991 [Pectobacterium aroidearum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T231380 NZ_CP090596:c515245-514991 [Pectobacterium aroidearum]
GTGAAGCTAATCTGGTCAGAAGAAGCATGGGAAGACTACCTGTACTGGCAGGACATCGATAAGCGGATGGTCAAAAAAAT
CAATGAATTAATAAAAGAAACGCGCAGAACACCTTTTGAGGGAAAAGGAAAACCAGAGCCACTTAAACATAATCTTGCTG
GTTTCTGGTCGCGCCGTATCACCGAAGAACATCGTCTGGTTTATGCCATCACCGATGACGCCATGATGATCGCTGCCTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT231380 WP_039324900.1 NZ_CP090596:c515493-515242 [Pectobacterium aroidearum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT231380 NZ_CP090596:c515493-515242 [Pectobacterium aroidearum]
ATGCGTACAATTAGCTACAGTGAAGCCCGACAAAATCTATCGGCGACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACTCGACAGAATGGTGAAGCCTGCGTGCTCATGTCTTTGGAAGAATATAACTCTCTAGAGGAGACCGCGTATT
TACTGCGTTCACCAGCAAATGCAAAAAGACTGATGAACTCAATCGAGAGCCTTAAAGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References