Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 514994..515496 Replicon chromosome
Accession NZ_CP090595
Organism Pectobacterium aroidearum strain QJ011

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag L0Y21_RS02250 Protein ID WP_039282578.1
Coordinates 514994..515248 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag L0Y21_RS02255 Protein ID WP_039324900.1
Coordinates 515245..515496 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y21_RS02230 (L0Y21_02230) 510152..511414 - 1263 WP_181845053.1 L-rhamnose isomerase -
L0Y21_RS02235 (L0Y21_02235) 511411..512901 - 1491 WP_256599337.1 rhamnulokinase -
L0Y21_RS02240 (L0Y21_02240) 513237..514076 + 840 WP_180778897.1 HTH-type transcriptional activator RhaS -
L0Y21_RS02245 (L0Y21_02245) 514101..514955 + 855 WP_181845054.1 helix-turn-helix domain-containing protein -
L0Y21_RS02250 (L0Y21_02250) 514994..515248 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
L0Y21_RS02255 (L0Y21_02255) 515245..515496 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
L0Y21_RS02260 (L0Y21_02260) 515572..517281 - 1710 WP_256599338.1 ABC transporter ATP-binding protein -
L0Y21_RS02265 (L0Y21_02265) 517278..518144 - 867 WP_010285293.1 ABC transporter permease -
L0Y21_RS02270 (L0Y21_02270) 518137..519096 - 960 WP_256599339.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T231370 WP_039282578.1 NZ_CP090595:c515248-514994 [Pectobacterium aroidearum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T231370 NZ_CP126343:1830967-1831221 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT231370 WP_039324900.1 NZ_CP090595:c515496-515245 [Pectobacterium aroidearum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT231370 NZ_CP126343:1830719-1830970 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References