Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4274078..4274580 Replicon chromosome
Accession NZ_CP090590
Organism Pectobacterium aroidearum strain QJ315

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag L0Y23_RS19090 Protein ID WP_039282578.1
Coordinates 4274326..4274580 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag L0Y23_RS19085 Protein ID WP_039324900.1
Coordinates 4274078..4274329 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y23_RS19070 (L0Y23_19050) 4270478..4271437 + 960 WP_012773138.1 ABC transporter permease -
L0Y23_RS19075 (L0Y23_19055) 4271430..4272296 + 867 WP_181829899.1 ABC transporter permease -
L0Y23_RS19080 (L0Y23_19060) 4272293..4274002 + 1710 WP_256542474.1 ABC transporter ATP-binding protein -
L0Y23_RS19085 (L0Y23_19065) 4274078..4274329 + 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
L0Y23_RS19090 (L0Y23_19070) 4274326..4274580 + 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
L0Y23_RS19095 (L0Y23_19075) 4274640..4275494 - 855 WP_256542475.1 helix-turn-helix domain-containing protein -
L0Y23_RS19100 (L0Y23_19080) 4275519..4276358 - 840 WP_194431515.1 HTH-type transcriptional activator RhaS -
L0Y23_RS19105 (L0Y23_19085) 4276694..4278184 + 1491 WP_256542476.1 rhamnulokinase -
L0Y23_RS19110 (L0Y23_19090) 4278181..4279443 + 1263 WP_181845053.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T231314 WP_039282578.1 NZ_CP090590:4274326-4274580 [Pectobacterium aroidearum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T231314 NZ_CP126329:872713-873120 [Citrobacter braakii]
GTGGTCCAGTGGCAATCTGATTTACGCGTTTCATGGCGCGCGCAATGGCTTTCGCTGCTCATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTCTGCTCTCTCTGGTGGTGTTCGATAGCG
TCCGTAGCCAGCGCCGAATCAATGCCTGTCAGGGCGAGATTCGGCTGTTGATGGACGGTCGTCTGCGCTGGCAAGGGCAA
GAGTGGACTATTGCTAGCGCACCCTGGATGGTCAAAACAGGCATGATGCTGCGTTTACGTTCCGATGCCGGAAAACGTCA
GCATTTGTGGCTGGCGGCAGACAGTATGGATGACGCGGAGTGGCGGGATTTGCGGCGGTTAATACTGCAACAGGCGAAGC
AGGGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT231314 WP_039324900.1 NZ_CP090590:4274078-4274329 [Pectobacterium aroidearum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT231314 NZ_CP126329:872466-872732 [Citrobacter braakii]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGTCGCGGTATGCGTGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGACT
TATTTAACTGGTTGATGAATCATGGGAAACCGGCTGATGCTCAGCTAGAGCAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References