Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 25740..26412 | Replicon | chromosome |
Accession | NZ_CP090588 | ||
Organism | Pectobacterium aroidearum strain AK042 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | L0Y25_RS00115 | Protein ID | WP_180779426.1 |
Coordinates | 26026..26412 (-) | Length | 129 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | L0Y25_RS00110 | Protein ID | WP_180779427.1 |
Coordinates | 25740..26039 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y25_RS00090 (L0Y25_00090) | 20975..21982 | + | 1008 | WP_256554064.1 | nucleoside hydrolase | - |
L0Y25_RS00095 (L0Y25_00095) | 21982..22959 | + | 978 | WP_012772765.1 | ABC transporter permease | - |
L0Y25_RS00100 (L0Y25_00100) | 22956..23864 | + | 909 | WP_256554065.1 | ABC transporter permease | - |
L0Y25_RS00105 (L0Y25_00105) | 23904..25703 | + | 1800 | WP_256554066.1 | ABC transporter ATP-binding protein | - |
L0Y25_RS00110 (L0Y25_00110) | 25740..26039 | - | 300 | WP_180779427.1 | XRE family transcriptional regulator | Antitoxin |
L0Y25_RS00115 (L0Y25_00115) | 26026..26412 | - | 387 | WP_180779426.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
L0Y25_RS00120 (L0Y25_00120) | 26628..27125 | + | 498 | WP_256554067.1 | GNAT family N-acetyltransferase | - |
L0Y25_RS00125 (L0Y25_00125) | 27325..27582 | - | 258 | WP_225181734.1 | DUF1471 domain-containing protein | - |
L0Y25_RS00130 (L0Y25_00130) | 27755..28555 | - | 801 | WP_194431341.1 | aliphatic sulfonates ABC transporter ATP-binding protein | - |
L0Y25_RS00135 (L0Y25_00135) | 28552..29346 | - | 795 | WP_180779424.1 | aliphatic sulfonate ABC transporter permease SsuC | - |
L0Y25_RS00140 (L0Y25_00140) | 29357..30499 | - | 1143 | WP_180779423.1 | FMNH2-dependent alkanesulfonate monooxygenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14834.84 Da Isoelectric Point: 4.7331
>T231277 WP_180779426.1 NZ_CP090588:c26412-26026 [Pectobacterium aroidearum]
MEVYRLAWEIVTRALFDTWFDEQTETVQEEVLAHLGILEEDGPQLGRPQVDQIKGSQYKNMKELRVQVGGHPFRTFFAFD
RTRKAIVLCAGDKKGENEKLFYERMIKIADAEFTSHLISPEVKEDGDI
MEVYRLAWEIVTRALFDTWFDEQTETVQEEVLAHLGILEEDGPQLGRPQVDQIKGSQYKNMKELRVQVGGHPFRTFFAFD
RTRKAIVLCAGDKKGENEKLFYERMIKIADAEFTSHLISPEVKEDGDI
Download Length: 387 bp
>T231277 NZ_CP126308:281590-281976 [Bosea vestrisii]
ATGGTGATCGACACGTCCGCGATCGTCGCGATCTTCTTCAATGAGCCGGATGCCCCGCGCTATCGCGAGCGCATCGCCGA
TGATCCCGTCCGGCTCATGTCGGCAGCGACGCTCCTTGAGGCCGCGATGGTTATCGAGGGGCGCTTCGGCGAGGCCGGCG
GCGCAGAGCTCGATCTGTGGCTGCACAAGGCCGAGGTCGAGATCGTCGCGGTGACCGCCGAGCACGCCGATCAGGCTCGG
CGTGCCTGGCGCCGCTACGGCAAGGGCCGCCACCCGGCCAGCCTGAACTACGGCGACTGCTTTTCCTATGCCCTCGCCGC
TTTGACGGGCGAGCCCCTGCTGTTCAAGGGCGAGGATTTCGCCCAGACCGACATCCAGGTAGCCTGA
ATGGTGATCGACACGTCCGCGATCGTCGCGATCTTCTTCAATGAGCCGGATGCCCCGCGCTATCGCGAGCGCATCGCCGA
TGATCCCGTCCGGCTCATGTCGGCAGCGACGCTCCTTGAGGCCGCGATGGTTATCGAGGGGCGCTTCGGCGAGGCCGGCG
GCGCAGAGCTCGATCTGTGGCTGCACAAGGCCGAGGTCGAGATCGTCGCGGTGACCGCCGAGCACGCCGATCAGGCTCGG
CGTGCCTGGCGCCGCTACGGCAAGGGCCGCCACCCGGCCAGCCTGAACTACGGCGACTGCTTTTCCTATGCCCTCGCCGC
TTTGACGGGCGAGCCCCTGCTGTTCAAGGGCGAGGATTTCGCCCAGACCGACATCCAGGTAGCCTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11082.10 Da Isoelectric Point: 10.6442
>AT231277 WP_180779427.1 NZ_CP090588:c26039-25740 [Pectobacterium aroidearum]
MATFKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL
MATFKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GKLTLDVTLPDGKRIALTL
Download Length: 300 bp
>AT231277 NZ_CP126308:281336-281590 [Bosea vestrisii]
ATGGCGCTAAGCATCAAAGACCCGAAGACCGAGAAGCTGGCGCGCGCCCTCGCCGAGCGCACGGGCGAGACCATCACCGT
CGCGACACGCCGGGCGATCGAGGAGCGCCTGAAGCGAATGGCGTCGCAAGGCCGCAAGGCAGCGCTCCTCGAGGACATGG
AGGCCATGCAACGGCGTTTGGATGCGCTGCCGGTGCTCGACCCCCGCAGCCCCGATGACATCATCGGCTACGACGAGAAC
GGCGTTCCGAACTAA
ATGGCGCTAAGCATCAAAGACCCGAAGACCGAGAAGCTGGCGCGCGCCCTCGCCGAGCGCACGGGCGAGACCATCACCGT
CGCGACACGCCGGGCGATCGAGGAGCGCCTGAAGCGAATGGCGTCGCAAGGCCGCAAGGCAGCGCTCCTCGAGGACATGG
AGGCCATGCAACGGCGTTTGGATGCGCTGCCGGTGCTCGACCCCCGCAGCCCCGATGACATCATCGGCTACGACGAGAAC
GGCGTTCCGAACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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