Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 1734003..1734570 | Replicon | chromosome |
| Accession | NZ_CP090508 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv11 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | LZ758_RS08150 | Protein ID | WP_004085174.1 |
| Coordinates | 1734003..1734284 (+) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | graA | Uniprot ID | - |
| Locus tag | LZ758_RS08155 | Protein ID | WP_004085172.1 |
| Coordinates | 1734295..1734570 (+) | Length | 92 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ758_RS08120 (LZ758_08120) | 1729183..1729581 | - | 399 | WP_234509046.1 | phage tail sheath C-terminal domain-containing protein | - |
| LZ758_RS08125 (LZ758_08125) | 1729550..1730359 | - | 810 | WP_234509048.1 | phage tail sheath family protein | - |
| LZ758_RS08130 (LZ758_08130) | 1730424..1732016 | - | 1593 | WP_040123119.1 | tail fiber domain-containing protein | - |
| LZ758_RS08135 (LZ758_08135) | 1732024..1732581 | - | 558 | WP_027700436.1 | phage tail protein I | - |
| LZ758_RS08140 (LZ758_08140) | 1732574..1733467 | - | 894 | WP_234056296.1 | baseplate J/gp47 family protein | - |
| LZ758_RS08145 (LZ758_08145) | 1733467..1733790 | - | 324 | WP_228304176.1 | GPW/gp25 family protein | - |
| LZ758_RS08150 (LZ758_08150) | 1734003..1734284 | + | 282 | WP_004085174.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZ758_RS08155 (LZ758_08155) | 1734295..1734570 | + | 276 | WP_004085172.1 | HigA family addiction module antitoxin | Antitoxin |
| LZ758_RS08160 (LZ758_08160) | 1734658..1734960 | + | 303 | WP_038230541.1 | type II toxin-antitoxin system MqsR family toxin | - |
| LZ758_RS08165 (LZ758_08165) | 1734963..1735364 | + | 402 | WP_004090697.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
| LZ758_RS08170 (LZ758_08170) | 1735433..1736020 | - | 588 | WP_040123117.1 | phage baseplate assembly protein V | - |
| LZ758_RS08175 (LZ758_08175) | 1736017..1736559 | - | 543 | WP_038230164.1 | hypothetical protein | - |
| LZ758_RS08180 (LZ758_08180) | 1736535..1737056 | - | 522 | WP_038230165.1 | hypothetical protein | - |
| LZ758_RS08185 (LZ758_08185) | 1737053..1737376 | - | 324 | WP_027700441.1 | hypothetical protein | - |
| LZ758_RS08190 (LZ758_08190) | 1737327..1737635 | - | 309 | WP_234056295.1 | hypothetical protein | - |
| LZ758_RS08195 (LZ758_08195) | 1737653..1738453 | - | 801 | WP_234509132.1 | phage major capsid protein | - |
| LZ758_RS08200 (LZ758_08200) | 1738522..1738950 | - | 429 | WP_234509050.1 | hypothetical protein | - |
| LZ758_RS08205 (LZ758_08205) | 1738947..1739525 | - | 579 | WP_234509053.1 | HK97 family phage prohead protease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1724271..1764549 | 40278 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10610.17 Da Isoelectric Point: 9.8829
>T230948 WP_004085174.1 NZ_CP090508:1734003-1734284 [Xylella fastidiosa subsp. morus]
MIKSFRHKGIQQFFLVGSTAGIQTKHAAKLRIQLTALESAKRPEDMNAPGWKLHPLKGADLKGHWSIWVNGNYRLTFAFE
GEDAILVDYQDYH
MIKSFRHKGIQQFFLVGSTAGIQTKHAAKLRIQLTALESAKRPEDMNAPGWKLHPLKGADLKGHWSIWVNGNYRLTFAFE
GEDAILVDYQDYH
Download Length: 282 bp
>T230948 NZ_CP125731:c3764690-3764292 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
Antitoxin
Download Length: 92 a.a. Molecular weight: 10072.68 Da Isoelectric Point: 10.2184
>AT230948 WP_004085172.1 NZ_CP090508:1734295-1734570 [Xylella fastidiosa subsp. morus]
MKRMHNPAHPGEVLREYLGELTVTNAAAKLGVSRVALSRILNGTNGISADMALRLEDALGTSAEMWAAMQFKYDLWVASQ
QPRPKITRLHV
MKRMHNPAHPGEVLREYLGELTVTNAAAKLGVSRVALSRILNGTNGISADMALRLEDALGTSAEMWAAMQFKYDLWVASQ
QPRPKITRLHV
Download Length: 276 bp
>AT230948 NZ_CP125731:c3764986-3764693 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|