Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 1772895..1773601 | Replicon | chromosome |
| Accession | NZ_CP090506 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv19 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | A0A060HKF7 |
| Locus tag | LZ757_RS08435 | Protein ID | WP_038230541.1 |
| Coordinates | 1772895..1773197 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | Q87EE1 |
| Locus tag | LZ757_RS08440 | Protein ID | WP_004090697.1 |
| Coordinates | 1773200..1773601 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ757_RS08405 (LZ757_08405) | 1768661..1770253 | - | 1593 | WP_040123119.1 | tail fiber domain-containing protein | - |
| LZ757_RS08410 (LZ757_08410) | 1770261..1770818 | - | 558 | WP_027700436.1 | phage tail protein I | - |
| LZ757_RS08415 (LZ757_08415) | 1770811..1771704 | - | 894 | WP_234056296.1 | baseplate J/gp47 family protein | - |
| LZ757_RS08420 (LZ757_08420) | 1771704..1772027 | - | 324 | WP_228304176.1 | GPW/gp25 family protein | - |
| LZ757_RS08425 (LZ757_08425) | 1772240..1772521 | + | 282 | WP_004085174.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZ757_RS08430 (LZ757_08430) | 1772532..1772807 | + | 276 | WP_004085172.1 | HigA family addiction module antitoxin | - |
| LZ757_RS08435 (LZ757_08435) | 1772895..1773197 | + | 303 | WP_038230541.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| LZ757_RS08440 (LZ757_08440) | 1773200..1773601 | + | 402 | WP_004090697.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| LZ757_RS08445 (LZ757_08445) | 1773670..1774257 | - | 588 | WP_040123117.1 | phage baseplate assembly protein V | - |
| LZ757_RS08450 (LZ757_08450) | 1774254..1774796 | - | 543 | WP_038230164.1 | hypothetical protein | - |
| LZ757_RS08455 (LZ757_08455) | 1774772..1775293 | - | 522 | WP_038230165.1 | hypothetical protein | - |
| LZ757_RS08460 (LZ757_08460) | 1775290..1775613 | - | 324 | WP_027700441.1 | hypothetical protein | - |
| LZ757_RS08465 (LZ757_08465) | 1775613..1775873 | - | 261 | WP_027700442.1 | hypothetical protein | - |
| LZ757_RS08470 (LZ757_08470) | 1775891..1777765 | - | 1875 | WP_038230171.1 | phage major capsid protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1752103..1802800 | 50697 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10972.77 Da Isoelectric Point: 8.0251
>T230934 WP_038230541.1 NZ_CP090506:1772895-1773197 [Xylella fastidiosa subsp. morus]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCAVVLALTSADFYKSMTTYTDHTLFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCAVVLALTSADFYKSMTTYTDHTLFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T230934 NZ_CP125731:c622579-622115 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGTTCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGTTCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14944.02 Da Isoelectric Point: 7.1650
>AT230934 WP_004090697.1 NZ_CP090506:1773200-1773601 [Xylella fastidiosa subsp. morus]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
Download Length: 402 bp
>AT230934 NZ_CP125731:c622914-622579 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A060HKF7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | Q87EE1 |