Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2597415..2597584 Replicon chromosome
Accession NZ_CP090407
Organism Staphylococcus aureus strain GD4SA159-1

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag LZ183_RS12890 Protein ID WP_224719344.1
Coordinates 2597492..2597584 (-) Length 31 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2597415..2597475 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ183_RS12875 (LZ183_12855) 2592869..2593036 - 168 WP_001798790.1 hypothetical protein -
LZ183_RS12880 (LZ183_12860) 2593267..2595000 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
LZ183_RS12885 (LZ183_12865) 2595025..2596788 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2597415..2597475 + 61 - - Antitoxin
LZ183_RS12890 (LZ183_12870) 2597492..2597584 - 93 WP_224719344.1 type I toxin-antitoxin system Fst family toxin Toxin
LZ183_RS12895 (LZ183_12875) 2597733..2598119 - 387 WP_000779355.1 flippase GtxA -
LZ183_RS12900 (LZ183_12880) 2598386..2599528 + 1143 WP_001176859.1 glycerate kinase -
LZ183_RS12905 (LZ183_12885) 2599588..2600247 + 660 WP_000831300.1 hypothetical protein -
LZ183_RS12910 (LZ183_12890) 2600435..2601646 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
LZ183_RS12915 (LZ183_12895) 2601769..2602242 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3393.97 Da        Isoelectric Point: 10.4935

>T230697 WP_224719344.1 NZ_CP090407:c2597584-2597492 [Staphylococcus aureus]
IDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 93 bp

>T230697 NZ_CP125334:2008190-2008292 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT230697 NZ_CP090407:2597415-2597475 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References