Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2551532..2551701 Replicon chromosome
Accession NZ_CP090375
Organism Staphylococcus aureus strain GD4SA108-1

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag LZ178_RS12505 Protein ID WP_224719344.1
Coordinates 2551609..2551701 (-) Length 31 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2551532..2551592 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ178_RS12490 (LZ178_12470) 2546986..2547153 - 168 WP_001798790.1 hypothetical protein -
LZ178_RS12495 (LZ178_12475) 2547384..2549117 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
LZ178_RS12500 (LZ178_12480) 2549142..2550905 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2551532..2551592 + 61 - - Antitoxin
LZ178_RS12505 (LZ178_12485) 2551609..2551701 - 93 WP_224719344.1 type I toxin-antitoxin system Fst family toxin Toxin
LZ178_RS12510 (LZ178_12490) 2551850..2552236 - 387 WP_000779355.1 flippase GtxA -
LZ178_RS12515 (LZ178_12495) 2552503..2553645 + 1143 WP_001176859.1 glycerate kinase -
LZ178_RS12520 (LZ178_12500) 2553705..2554364 + 660 WP_000831300.1 hypothetical protein -
LZ178_RS12525 (LZ178_12505) 2554552..2555763 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
LZ178_RS12530 (LZ178_12510) 2555886..2556359 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3393.97 Da        Isoelectric Point: 10.4935

>T230510 WP_224719344.1 NZ_CP090375:c2551701-2551609 [Staphylococcus aureus]
IDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 93 bp

>T230510 NZ_CP124914:c295959-295864 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA

Antitoxin


Download         Length: 61 bp

>AT230510 NZ_CP090375:2551532-2551592 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References