Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1950529..1951235 Replicon chromosome
Accession NZ_CP090316
Organism Xylella fastidiosa subsp. morus strain Riv16

Toxin (Protein)


Gene name mqsR Uniprot ID A0A060HKF7
Locus tag IUD23_RS08770 Protein ID WP_038230541.1
Coordinates 1950933..1951235 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID Q87EE1
Locus tag IUD23_RS08765 Protein ID WP_004090697.1
Coordinates 1950529..1950930 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUD23_RS08735 (IUD23_08735) 1946366..1948240 + 1875 WP_038230171.1 phage major capsid protein -
IUD23_RS08740 (IUD23_08740) 1948258..1948566 + 309 WP_234056295.1 hypothetical protein -
IUD23_RS08745 (IUD23_08745) 1948517..1948840 + 324 WP_027700441.1 hypothetical protein -
IUD23_RS08750 (IUD23_08750) 1948837..1949358 + 522 WP_038230165.1 hypothetical protein -
IUD23_RS08755 (IUD23_08755) 1949334..1949876 + 543 WP_038230164.1 hypothetical protein -
IUD23_RS08760 (IUD23_08760) 1949873..1950460 + 588 WP_040123117.1 phage baseplate assembly protein V -
IUD23_RS08765 (IUD23_08765) 1950529..1950930 - 402 WP_004090697.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
IUD23_RS08770 (IUD23_08770) 1950933..1951235 - 303 WP_038230541.1 type II toxin-antitoxin system MqsR family toxin Toxin
IUD23_RS08775 (IUD23_08775) 1951323..1951598 - 276 WP_004085172.1 HigA family addiction module antitoxin -
IUD23_RS08780 (IUD23_08780) 1951609..1951890 - 282 WP_004085174.1 type II toxin-antitoxin system RelE/ParE family toxin -
IUD23_RS08785 (IUD23_08785) 1952103..1952426 + 324 WP_228304176.1 GPW/gp25 family protein -
IUD23_RS08790 (IUD23_08790) 1952426..1953319 + 894 WP_234056296.1 baseplate J/gp47 family protein -
IUD23_RS08795 (IUD23_08795) 1953312..1953869 + 558 WP_027700436.1 phage tail protein I -
IUD23_RS08800 (IUD23_08800) 1953877..1955469 + 1593 WP_040123119.1 tail fiber domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1921681..1968040 46359


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10972.77 Da        Isoelectric Point: 8.0251

>T230430 WP_038230541.1 NZ_CP090316:c1951235-1950933 [Xylella fastidiosa subsp. morus]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCAVVLALTSADFYKSMTTYTDHTLFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp

>T230430 NZ_CP124895:70415-70525 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14944.02 Da        Isoelectric Point: 7.1650

>AT230430 WP_004090697.1 NZ_CP090316:c1950930-1950529 [Xylella fastidiosa subsp. morus]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS

Download         Length: 402 bp

>AT230430 NZ_CP124895:c70629-70565 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A060HKF7

Antitoxin

Source ID Structure
AlphaFold DB Q87EE1

References